Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 9/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 7/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10042868 | 0.93 | MTNR1A (0.51) | ACHEHSD17B2HSD17B1MAOBMTNR1A | |
| SCHEMBL13929902 | 0.92 | ACHE (0.48) | ACHEHSD17B2HSD17B1MAOBMTNR1A | |
| SCHEMBL9581416 | 0.92 | ACHE (0.48) | ACHEHSD17B2HSD17B1MAOBMTNR1A | |
| SCHEMBL18350097 | 0.92 | ACHE (0.58) | ACHEHSD17B2HSD17B1MAOBMTNR1A | |
| SCHEMBL14570731 | 0.92 | ACHE (0.48) | ACHE | |
| SCHEMBL18052478 | 0.92 | ACHE (0.48) | ACHEHSD17B2HSD17B1MAOBMTNR1A | |
| SCHEMBL13152209 | 0.92 | ACHE (0.48) | ACHE | |
| SCHEMBL8497577 | 0.92 | ACHE (0.67) | ACHEHSD17B2HSD17B1MAOBMTNR1A | |
| SCHEMBL9770735 | 0.92 | HSD17B2 (0.47) | ACHEHSD17B2HSD17B1MAOBMTNR1A | |
| SCHEMBL19955901 | 0.92 | ACHE (0.47) | ACHEHSD17B2HSD17B1MAOBMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |