SCHEMBL9915736

SCHEMBL9915736

C=CC(=O)OC(CCC)OC(=O)Oc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(OC(=O)OC(CCC)OC(=O)C=C)cc3)c(C)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.39
MAPT P10636 5/20 0.35
KMT2A Q03164 4/20 0.35
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
MAPK1 P28482 1/20 0.35
TAS1R3 Q7RTX0 3/20 0.34
TAS1R1 Q7RTX1 3/20 0.34
LMNA P02545 1/20 0.33
PRSS1 P07477 2/20 0.33
TMPRSS15 P98073 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MGLL Q99685 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ACR P10323 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12950565 0.93 L3MBTL1 (0.41) THRBMAPTKMT2ATAS1R3TAS1R1
SCHEMBL13283122 0.90 THRB (0.38) THRBMAPTKMT2AKDM4EPOLB
SCHEMBL12806669 0.88 THRB (0.40) THRBMAPTKMT2AKDM4EPOLB
SCHEMBL12806618 0.88 TAS1R3 (0.38) THRBMAPTKMT2AKDM4EMAPK1
SCHEMBL8962274 0.85 MAPT (0.37) THRBMAPTKMT2AKDM4EPOLB
SCHEMBL9908889 0.85 THRB (0.39) THRBMAPTKMT2AKDM4EPOLB
SCHEMBL10042168 0.83 MAPT (0.38) THRBMAPTKMT2AKDM4EPOLB
SCHEMBL14068880 0.83 THRB (0.41) THRBMAPTKMT2AKDM4EPOLB
SCHEMBL10042216 0.83 THRB (0.43) THRBMAPTKMT2AKDM4EPOLB
SCHEMBL12618295 0.82 THRB (0.36) THRBMAPTKMT2ALMNAPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8199291-B2 Liquid crystal display device having polymer-stabilized blue phase liquid crystal layer and transparent films FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
US-8025936-B2 Optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-09-27 US disclosed
US-7876502-B2 Optical film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2011-01-25 US disclosed
US-20100142055-A1 OPTICAL ELEMENT, DIRECTIONAL DIFFUSION FILM, AND METHOD OF MANUFACTURING OPTICAL ELEMENT NITTO DENKO CORPORATION (JP) 2010-06-10 US disclosed
US-20090322997-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-12-31 US disclosed
US-20090091690-A1 Optical Compensation Film, Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-04-09 US disclosed
US-20090052032-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2009-02-26 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed