SCHEMBL9915802

SCHEMBL9915802

C=C(C)C(=O)Oc1ccc(N(c2ccc(OC(=O)C(=C)C)cc2)c2ccc(OC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.57
KMT2A Q03164 5/20 0.53
ATM Q13315 1/20 0.53
MEN1 O00255 2/20 0.41
RAB9A P51151 2/20 0.41
LMNA P02545 1/20 0.39
MAPT P10636 2/20 0.39
ALDH1A1 P00352 1/20 0.37
NPSR1 Q6W5P4 2/20 0.37
POLB P06746 2/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
HSD17B10 Q99714 2/20 0.36
PKM P14618 1/20 0.36
NPC1 O15118 1/20 0.36
SRD5A1 P18405 1/20 0.35
THRB P10828 1/20 0.35
ESR1 P03372 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2623396 0.95 ELANE (0.53) ELANEKMT2AATMMEN1RAB9A
SCHEMBL12234115 0.93 ELANE (0.51) ELANEKMT2AATMMEN1RAB9A
SCHEMBL172511 0.93 ELANE (0.64) ELANEKMT2AATMMEN1RAB9A
SCHEMBL12234109 0.93 LMNA (0.52) ELANEKMT2AATMMEN1RAB9A
SCHEMBL9915684 0.93 ELANE (0.64) ELANEKMT2AATMMEN1RAB9A
SCHEMBL9915685 0.93 LMNA (0.52) ELANEKMT2AATMMEN1RAB9A
SCHEMBL12234119 0.92 ELANE (0.50) ELANEKMT2AATMMEN1LMNA
SCHEMBL11987118 0.90 THRB (0.50) ELANEKMT2AATMMEN1RAB9A
SCHEMBL12234118 0.90 ELANE (0.49) ELANEKMT2AATMMEN1RAB9A
SCHEMBL11987119 0.90 THRB (0.50) ELANEKMT2AATMMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 US disclosed
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 US disclosed
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-8335456-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2012-12-18 US disclosed
US-8247143-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2012-08-21 US disclosed
US-8197997-B2 Electrophotographic photoconductor, production method thereof, image forming method and image forming apparatus using photoconductor, and process cartridge RICOH COMPANY, LTD. (JP) 2012-06-12 US disclosed
US-8197997-B2 Electrophotographic photoconductor, production method thereof, image forming method and image forming apparatus using photoconductor, and process cartridge RICOH COMPANY, LTD. (JP) 2012-06-12 US disclosed
US-8114563-B2 Forming photosensitive layer on electroconductive substrate wherein the crosslinked surface layer has a surface roughness (Ra) not greater than 0.2 mu m and a peel strength not less than 0.2 N/mm; durability, stable electrical properties, good cleanability, and producing high-quality images RICOH COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-8114563-B2 Forming photosensitive layer on electroconductive substrate wherein the crosslinked surface layer has a surface roughness (Ra) not greater than 0.2 mu m and a peel strength not less than 0.2 N/mm; durability, stable electrical properties, good cleanability, and producing high-quality images RICOH COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-20080153021-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-06-26 US disclosed
US-20080138725-A1 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY LIMITED (JP) 2008-06-12 US disclosed
US-20080138725-A1 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY LIMITED (JP) 2008-06-12 US disclosed
US-20080124638-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-05-29 US disclosed
US-20080124638-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-05-29 US disclosed
US-20080038649-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LIMITED (JP) 2008-02-14 US disclosed
US-20080038649-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LIMITED (JP) 2008-02-14 US disclosed
US-20070297836-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-12-27 US disclosed
US-20070212627-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
US-20070212627-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed