SCHEMBL2623396

SCHEMBL2623396

C=C(C)C(=O)Oc1ccc(-c2ccc(N(c3ccc(-c4ccc(OC(=O)C(=C)C)cc4)cc3)c3ccc(-c4ccc(OC(=O)C(=C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.53
KMT2A Q03164 3/20 0.49
ATM Q13315 1/20 0.49
HSD17B10 Q99714 3/20 0.42
MEN1 O00255 1/20 0.38
GFER P55789 1/20 0.37
RAB9A P51151 2/20 0.37
LMNA P02545 2/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 3/20 0.36
NPSR1 Q6W5P4 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
POLB P06746 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
ALDH1A1 P00352 1/20 0.33
PKM P14618 1/20 0.33
NPC1 O15118 1/20 0.33
KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9915802 0.95 ELANE (0.57) ELANEKMT2AATMHSD17B10MEN1
SCHEMBL13837348 0.94 ELANE (0.59) ELANEKMT2AATMHSD17B10MEN1
SCHEMBL9915701 0.94 ELANE (0.48) ELANEKMT2AATMHSD17B10MEN1
SCHEMBL11987034 0.94 ELANE (0.48) ELANEKMT2AATMHSD17B10MEN1
SCHEMBL172483 0.94 ELANE (0.59) ELANEKMT2AATMHSD17B10MEN1
SCHEMBL10020858 0.94 ELANE (0.59) ELANEKMT2AATMHSD17B10MEN1
SCHEMBL9915703 0.94 ELANE (0.48) ELANEKMT2AATMHSD17B10MEN1
SCHEMBL2543494 0.94 ELANE (0.59) ELANEKMT2AATMHSD17B10MEN1
SCHEMBL9915687 0.94 ELANE (0.59) ELANEKMT2AATMHSD17B10MEN1
SCHEMBL11987044 0.94 ELANE (0.59) ELANEKMT2AATMHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150079714-A1 COMPOSITION FOR USE IN ORGANIC DEVICE, POLYMER FILM, AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2015-03-19 US disclosed
US-20150079714-A1 COMPOSITION FOR USE IN ORGANIC DEVICE, POLYMER FILM, AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2015-03-19 US disclosed
EP-2112702-B1 ORGANIC ELECTROLUMINESCENT DEVICE AND ITS METHOD FOR MANUFACTURING MITSUBISHI CHEM CORP (JP) 2014-06-18 EP disclosed
US-8222807-B2 Organic electroluminescence device and method of producing organic device MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-17 US disclosed
US-8222807-B2 Organic electroluminescence device and method of producing organic device MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-17 US disclosed
US-20120091443-A1 COMPOSITION FOR USE IN ORGANIC DEVICE, POLYMER FILM, AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2012-04-19 US disclosed
US-20120091443-A1 COMPOSITION FOR USE IN ORGANIC DEVICE, POLYMER FILM, AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2012-04-19 US disclosed
US-20110245429-A1 Cross Linked Organic Conductive Layer GOUGH, NEIL (GB) 2011-10-06 US disclosed
US-20110245429-A1 Cross Linked Organic Conductive Layer GOUGH, NEIL (GB) 2011-10-06 US disclosed
WO-2010068205-A1 CROSS LINKED ORGANIC CONDUCTIVE LAYER HCF PARTNERS, L.P. (US) 2010-06-17 WO disclosed
US-20100090590-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND METHOD OF PRODUCING ORGANIC DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2010-04-15 US disclosed
US-20100090590-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND METHOD OF PRODUCING ORGANIC DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2010-04-15 US disclosed
US-20100045174-A1 COMPOSITION FOR USE IN ORGANIC DEVICE, POLYMER FILM, AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2010-02-25 US disclosed
US-20100045174-A1 COMPOSITION FOR USE IN ORGANIC DEVICE, POLYMER FILM, AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2010-02-25 US disclosed
EP-2112702-A1 ORGANIC FIELD EMITTING ELEMENT AND METHOD FOR MANUFACTURING ORGANIC DEVICE Mitsubishi Chemical Corporation (JP) 2009-10-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245429-A1 Cross Linked Organic Conductive Layer GJB2, GJA1, KCNH3 ELANE 2842/4885KMT2A 1697/4885ATM 3033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.