Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | SGK1 | O00141 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.36 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.36 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.36 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21375272 | 0.96 | SMN1; SMN2 (0.38) | AKR1C3AKR1C2ESR1ESR2KDM4E | |
| SCHEMBL26415868 | 0.94 | AKR1C3 (0.40) | AKR1C3AKR1C2ESR1ESR2KDM4E | |
| SCHEMBL9916258 | 0.91 | KDM4E (0.43) | ESR2KDM4EATML3MBTL1DHFR | |
| SCHEMBL29516803 | 0.90 | ESR1 (0.47) | ESR1ESR2KDM4EATML3MBTL1 | |
| SCHEMBL10130160 | 0.90 | ESR1 (0.47) | ESR1ESR2KDM4EATML3MBTL1 | |
| SCHEMBL9916254 | 0.89 | KDM4E (0.53) | KDM4EATML3MBTL1DHFRSMN1; SMN2 | |
| SCHEMBL9916264 | 0.89 | KDM4E (0.53) | KDM4EATML3MBTL1DHFRSMN1; SMN2 | |
| SCHEMBL9916256 | 0.89 | KDM4E (0.53) | KDM4EATML3MBTL1DHFRSMN1; SMN2 | |
| SCHEMBL9916243 | 0.89 | KDM4E (0.53) | KDM4EATML3MBTL1DHFRSMN1; SMN2 | |
| SCHEMBL21076116 | 0.88 | SMN1; SMN2 (0.40) | ESR2KDM4EATML3MBTL1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170162790-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2017-06-08 | — | — | US | disclosed |
| US-9614160-B2 | Aromatic amine derivatives and organic electroluminescent elements using same | IDEMITSU KOSAN CO., LTD. (JP) | 2017-04-04 | — | — | US | disclosed |
| US-9614160-B2 | Aromatic amine derivatives and organic electroluminescent elements using same | IDEMITSU KOSAN CO., LTD. (JP) | 2017-04-04 | — | — | US | disclosed |
| US-20160064669-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2016-03-03 | — | — | US | disclosed |
| US-9260390-B2 | Aromatic amine derivatives and organic electroluminescent elements using same | IDEMITSU KOSAN CO., LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| US-20120146014-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170162790-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | RER1, NR4A1, REL | AKR1C3 936/4885AKR1C2 1122/4885ESR1 13/4885 |
| US-20120146014-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | PNMT, TYR, AOC2 | AKR1C3 4588/4885AKR1C2 3992/4885ESR1 54/4885 |
| US-20160064669-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | PNMT, TYR, AOC2 | AKR1C3 4588/4885AKR1C2 3992/4885ESR1 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.