SCHEMBL9917228

SCHEMBL9917228

COCOC(=O)c1ccc2c(c1)C(=O)c1ccccc1C2=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.59
▸ NPC1 O15118 4/20 0.59
▸ RAB9A P51151 4/20 0.59
▸ LMNA P02545 3/20 0.59
▸ SMN1; SMN2 Q16637 3/20 0.59
▸ ALDH1A1 P00352 3/20 0.59
▸ HTT P42858 1/20 0.54
▸ TTR P02766 2/20 0.54
▸ KDM4E B2RXH2 2/20 0.52
▸ CYP1A2 P05177 1/20 0.52
▸ CYP2D6 P10635 1/20 0.52
▸ CYP2C9 P11712 1/20 0.52
▸ CYP2C19 P33261 1/20 0.52
▸ PTPRC P08575 4/20 0.49
▸ S100A4 P26447 1/20 0.47
▸ ATM Q13315 1/20 0.47
▸ MAPK1 P28482 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ HTR7 P34969 1/20 0.46
▸ HTR2B P41595 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268884 0.84 MAPT (0.75) MAPTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL12195026 0.83 MAPT (0.54) MAPTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL2265496 0.82 TTR (0.62) MAPTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL23051434 0.82 ALDH1A1 (0.64) MAPTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL4921071 0.81 TTR (0.61) MAPTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL4919505 0.81 MAPT (0.62) MAPTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL20087546 0.80 MAPT (0.61) MAPTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL18118420 0.80 MAPT (0.61) MAPTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL2268427 0.80 MAPT (0.61) MAPTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL6933741 0.79 TTR (0.67) MAPTNPC1RAB9ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8541072-B2 UV cured heterogeneous intermediate transfer belts (ITB) XEROX CORPORATION (US) 2013-09-24 — — US disclosed
US-20120146265-A1 INTERMEDIATE TRANSFER MEMBER METHOD OF MANUFACTURE XEROX CORPORATION (US) 2012-06-14 — — US disclosed
US-20110123732-A1 UV CURED HETEROGENEOUS INTERMEDIATE TRANSFER BELTS (ITB) XEROX CORPORATION (US) 2011-05-26 — — US disclosed
US-7547472-B2 Polymer and method for using the polymer for noncovalently functionalizing nanotubes ZYVEX PERFORMANCE MATERIALS, INC. (US) 2009-06-16 — — US disclosed
US-7544415-B2 Polymer and method for using the polymer for solubilizing nanotubes ZYVEX PERFORMANCE MATERIALS, INC. (US) 2009-06-09 — — US disclosed
US-7479516-B2 Nanocomposites and methods thereto ZYVEX PERFORMANCE MATERIALS, LLC (US) 2009-01-20 — — US disclosed
US-20080194737-A1 functionalized, solubilized single-walled or multi-walled carbon nanotubes comprising polyacetylenes, polythiophenes or polypyrroles, mixed within fibrous materials such as paper; composites having improved tensile strength ZYVEX PERFORMANCE MATERIALS, LLC (US) 2008-08-14 — — US disclosed
US-20080187482-A1 Interacting a polymer and functional group to form a polymer having a backbone portion for noncovalently bonding with a nanotube in a non-wrapping fashion, interacting with a nanotube; flat-panel displays that use electron field-emission technology ZYVEX PERFORMANCE MATERIALS, LLC (US) 2008-08-07 — — US disclosed
US-7296576-B2 Polymers for enhanced solubility of nanomaterials, compositions and methods therefor ZYVEX PERFORMANCE MATERIALS, LLC (US) 2007-11-20 — — US disclosed
US-20070265379-A1 NANOCOMPOSITES AND METHODS THERETO ZYVEX CORPORATION (US) 2007-11-15 — — US disclosed
US-7244407-B2 Polymer and method for using the polymer for solubilizing nanotubes ZYVEX PERFORMANCE MATERIALS, LLC (US) 2007-07-17 — — US disclosed
US-7241496-B2 Polymer and method for using the polymer for noncovalently functionalizing nanotubes Zyvex Performance Materials, LLC. (US) 2007-07-10 — — US disclosed
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