Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.67 |
| ▸ | PTPRC | P08575 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | S100A4 | P26447 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934221 | 0.98 | TTR (0.65) | TTRPTPRCMAPTNPC1RAB9A | |
| SCHEMBL16731946 | 0.89 | TTR (0.58) | TTRPTPRCMAPTNPC1RAB9A | |
| SCHEMBL2265496 | 0.85 | TTR (0.62) | TTRPTPRCMAPTNPC1RAB9A | |
| SCHEMBL4921071 | 0.84 | TTR (0.61) | TTRPTPRCMAPTNPC1RAB9A | |
| SCHEMBL419916 | 0.83 | MAPT (0.61) | TTRPTPRCMAPTNPC1RAB9A | |
| SCHEMBL15082754 | 0.82 | TTR (0.59) | TTRPTPRCMAPTNPC1RAB9A | |
| SCHEMBL16731600 | 0.82 | S100A4 (0.59) | TTRPTPRCMAPTNPC1RAB9A | |
| SCHEMBL2268884 | 0.81 | MAPT (0.75) | TTRPTPRCMAPTNPC1RAB9A | |
| SCHEMBL18015981 | 0.81 | PTPRC (0.59) | TTRPTPRCMAPTNPC1RAB9A | |
| SCHEMBL26120300 | 0.80 | S100A4 (0.62) | TTRPTPRCMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-4329456-A | ACYLATION WITHOUT INTERMEDIATE ISOLATION | CIBA-GEIGY AG (CH) | 1982-05-11 | — | — | US | disclosed |
| US-4265633-A | Process for the manufacture of vat dyes | CIBA-GEIGY AG (CH) | 1981-05-05 | — | — | US | disclosed |