SCHEMBL991777

SCHEMBL991777

Oc1ccccc1-c1c(Cc2ccc3[nH]nnc3c2-c2ccccc2O)ccc2[nH]nnc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.36
HSPA5 P11021 1/20 0.35
GUSB P08236 1/20 0.33
MGAM O43451 2/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
DCUN1D1 Q96GG9 1/20 0.32
TTR P02766 1/20 0.32
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.32
RAB9A P51151 1/20 0.32
GFER P55789 1/20 0.31
ADORA2A P29274 1/20 0.31
ALOX15 P16050 1/20 0.31
HPGD P15428 1/20 0.31
BCL2L1 Q07817 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2731449 0.85 GABRA1 (0.38) IDO1GUSBGAADCUN1D1ALDH1A1
SCHEMBL11074239 0.84 ELANE (0.41) IDO1ALDH1A1MEN1KMT2ALMNA
SCHEMBL15020976 0.83 GCGR (0.42) GAAALDH1A1MEN1KMT2ALMNA
SCHEMBL11666453 0.82 ELANE (0.43) GAAALDH1A1MEN1KMT2ALMNA
SCHEMBL7451778 0.81 IDO1 (0.37) IDO1GUSBMGAMGAASI
SCHEMBL30117209 0.81 MEN1 (0.39) IDO1GUSBMGAMGAASI
SCHEMBL6064915 0.81 MEN1 (0.39) IDO1GUSBMGAMGAASI
SCHEMBL15020493 0.81 MGAM (0.41) IDO1GUSBMGAMGAASI
SCHEMBL8218667 0.79 HSPA5 (0.35) IDO1HSPA5GUSBMGAMGAA
SCHEMBL1628801 0.78 DPP4 (0.37) IDO1GUSBMGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 592 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3709966-B1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT OREAL (FR) 2024-12-11 EP claimed
EP-3393437-B1 PHOTOPROTECTIVE COMPOSITION BASED ON A CARBOXYLIC ACID ESTER; USE OF SAID COMPOUND FOR INCREASING THE SUN PROTECTION FACTOR OREAL (FR) 2023-06-07 EP claimed
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2022-07-21 US claimed
US-11344487-B2 Photoprotective compositions comprising a dibenzoylmethane derivative, a merocyanine compound and a compound capable of accepting the triplet excited level energy of the dibenzoylmethane compound L'OREAL (FR) 2022-05-31 US claimed
US-20200360264-A1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT L'OREAL (FR) 2020-11-19 US claimed
EP-3709966-A1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT L'Oreal (FR) 2020-09-23 EP claimed
US-20200261748-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING AN AQUEOUS PHASE AND A LOW MELTING POINT APOLAR WAX L'OREAL (FR) 2020-08-20 US claimed
EP-3193816-B1 COMPOSITION BASED ON MULTILAYER SPHERICAL COMPOSITE PARTICLES AND ON A UV-SCREENING AGENT OREAL (FR) 2020-05-13 EP claimed
US-20200138684-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2020-05-07 US claimed
EP-3644954-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'Oreal (FR) 2020-05-06 EP claimed
WO-2002049595-A2 FILTERING COMPOSITION CONTAINING A FILTER OF THE TYPE DERIVED FROM DIBENZOYLMETHANE AND A 4,4-DIARYLBUTADIENE TYPE FILTER L'OREAL (FR) 2002-06-27 WO claimed
WO-2002041867-A1 COLOURED SELF-TANNING COMPOSITIONS COMPRISING COCHINEAL CARMINE L'OREAL (FR) 2002-05-30 WO claimed
WO-2002019979-A2 COMPOSITION CONTAINING A DIBENZOYLMETHANE DERIVATIVE AND AN α-ALKYLSTYRENE DIMER, UV STABILISING METHOD L'OREAL (FR) 2002-03-14 WO claimed
EP-1093797-B1 Process for the photostabilisation of sunscreens derived from dibenzoylmethane by an insoluble organic filter OREAL (FR) 2002-02-20 EP claimed
EP-1172092-A1 Skin dyeing compositions containing at least an uv filter and a non substituted in position 3 flavylium salt L'OREAL (FR) 2002-01-16 EP claimed
WO-2001049686-A1 S-TRIAZINE DERIVATIVES AND THEIR USE AS UV FILTERS L'OREAL (FR) 2001-07-12 WO claimed
EP-1093796-A1 Emulsions containing one or more insoluble organic UV-filter and an associative polymer L'OREAL (FR) 2001-04-25 EP claimed
EP-1093799-A1 Water-in-Oil emulsions containing at least one insoluble organic UV filter and a non-filtrating organomodified silicone L'OREAL (FR) 2001-04-25 EP claimed
EP-1093798-A1 Emulsions without emulsifiers containing at least one insoluble organic UV-filter L'OREAL (FR) 2001-04-25 EP claimed
EP-1093797-A1 Process for the photostabilisation of sunscreens derived from dibenzoylmethane by an insoluble organic filter L'OREAL (FR) 2001-04-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200138684-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND DDT, ERCC5, ERCC1 IDO1 738/4885HSPA5 2413/4885GUSB 4804/4885
US-20200360264-A1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT PCNA, ERCC1, XRCC6 IDO1 4018/4885HSPA5 1221/4885GUSB 1144/4885
US-11344487-B2 Photoprotective compositions comprising a dibenzoylmethane derivative, a merocyanine compound and a compound capable of accepting the triplet excited level energy of the dibenzoylmethane compound DDT, ERCC5, ERCC1 IDO1 738/4885HSPA5 2413/4885GUSB 4804/4885
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND ERCC5, DDT, ERCC1 IDO1 731/4885HSPA5 1682/4885GUSB 4740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.