Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPBWR1 | P48145 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9917046 | 0.94 | ALDH1A1 (0.50) | NPSR1ALDH1A1MAPTPPARGNCOA2 | |
| SCHEMBL1462027 | 0.93 | NPSR1 (0.52) | NPSR1ALDH1A1MAPTPPARGNCOA2 | |
| SCHEMBL1461851 | 0.91 | ALDH1A1 (0.47) | NPSR1ALDH1A1MAPTPPARGNCOA2 | |
| SCHEMBL9918819 | 0.89 | NPSR1 (0.53) | NPSR1ALDH1A1MAPTPPARGNCOA2 | |
| SCHEMBL9896063 | 0.86 | NPC1 (0.51) | NPSR1ALDH1A1MAPTPPARGNCOA2 | |
| SCHEMBL1461433 | 0.85 | MAPT (0.41) | NPSR1ALDH1A1MAPTPPARGNCOA2 | |
| SCHEMBL9917036 | 0.82 | NPBWR1 (0.47) | NPSR1ALDH1A1MAPTPPARGNCOA2 | |
| SCHEMBL1460616 | 0.82 | GAA (0.54) | NPSR1ALDH1A1MAPTPPARGNCOA2 | |
| SCHEMBL1461679 | 0.82 | GAA (0.74) | NPSR1ALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL9917035 | 0.80 | NPBWR1 (0.39) | NPSR1ALDH1A1MAPTPPARGNCOA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149710-A1 | SORTASE A INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149710-A1 | SORTASE A INHIBITORS | STS, ENGASE, SPR | NPSR1 1796/4885ALDH1A1 2421/4885MAPT 3322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.