SCHEMBL991993

SCHEMBL991993

[c]1ccc2c(c1)C1(c3c[c]ccc3-2)c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
OPRK1 P41145 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PDK2 Q15119 1/20 0.34
ITGA4 P13612 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
S100A4 P26447 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3741162 1.00 KDM4E (0.41) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL7707020 1.00 KDM4E (0.41) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL827868 0.88 MEN1 (0.48) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL20816538 0.88 KDM4E (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL22635730 0.88 ALDH1A1 (0.36) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL20816532 0.88 MEN1 (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL18894017 0.87 KDM4E (0.41) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL6292314 0.87 KDM4E (0.41) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL20560404 0.83 ALOX5 (0.32)
SCHEMBL2233600 0.82 MEN1 (0.47) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2273512-B1 Conjugated polymers comprising triarylamine-arylenevinylene units, synthesis and use of the same MERCK PATENT GMBH (DE) 2016-07-20 EP claimed
EP-2273512-A2 Conjugated polymers comprising triarylamine-arylenevinylene units, synthesis and use of the same Merck Patent GmbH (DE) 2011-01-12 EP claimed
US-7799875-B2 polymeric light emitting diodes; longer operating lifetime; brightness with lower energy; MERCK PATENT GMBH (DE) 2010-09-21 US claimed
US-20090005505-A1 polymeric light emitting diodes; longer operating lifetime; brightness with lower energy; MERCK PATENT GMBH (DE) 2009-01-01 US claimed
EP-1961016-A1 TRIARYLAMINE-ARYLVINYLENE MOIETY-CONTAINING CONJUGATED POLYMERS, THEIR PRODUCTION AND USE Merck Patent GmbH (DE) 2008-08-27 EP claimed
WO-2007068325-A1 TRIARYLAMINE-ARYLVINYLENE MOIETY-CONTAINING CONJUGATED POLYMERS, THEIR PRODUCTION AND USE MERCK PATENT GMBH (DE) 2007-06-21 WO claimed
EP-0894107-B1 COMPOUNDS WITH SPIRO ATOMS AND THEIR USE AS ELECTROLUMINESCENT MATERIALS AVENTIS RES & TECH GMBH & CO (DE) 1999-12-22 EP claimed
US-20240147841-A1 Organic Semiconductive Layer Comprising Phosphine Oxide Compounds NOVALED GMBH (DE) 2024-05-02 US disclosed
US-20240122065-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN TOSOH CORPORATION (JP) 2024-04-11 US disclosed
US-11950496-B2 Organic semiconductive layer comprising phosphine oxide compounds NOVALED GMBH (DE) 2024-04-02 US disclosed
EP-4198163-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN Tosoh Corporation (JP) 2023-06-21 EP disclosed
CN-116157382-A Material for metal patterning, amine compound, electronic device, and method for forming metal pattern 东曹株式会社 2023-05-23 CN disclosed
WO-2023013697-A1 MATERIAL FOR METAL PATTERNING, FLUORO COMPOUND, THIN FILM FOR METAL PATTERNING, ORGANIC ELECTROLUMINESCENCE DEVICE, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN 東ソー株式会社 2023-02-09 WO disclosed
US-7799875-B2 polymeric light emitting diodes; longer operating lifetime; brightness with lower energy; MERCK PATENT GMBH (DE) 2010-09-21 US disclosed
US-20090005505-A1 polymeric light emitting diodes; longer operating lifetime; brightness with lower energy; MERCK PATENT GMBH (DE) 2009-01-01 US disclosed
EP-1961016-A1 TRIARYLAMINE-ARYLVINYLENE MOIETY-CONTAINING CONJUGATED POLYMERS, THEIR PRODUCTION AND USE Merck Patent GmbH (DE) 2008-08-27 EP disclosed
WO-2007068325-A1 TRIARYLAMINE-ARYLVINYLENE MOIETY-CONTAINING CONJUGATED POLYMERS, THEIR PRODUCTION AND USE MERCK PATENT GMBH (DE) 2007-06-21 WO disclosed
US-6504042-B1 Optic couplers, radiation measuring instruments, prisms and waveguides comprising armophous spirobi-9-silafluorenes or spirobifluorenes having solubility and stability HOECHST AKTIENGESELLSCHAFT (DE) 2003-01-07 US disclosed
US-5763636-A CONJUGATED POLYCYCLIC POLYMERS HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-09 US disclosed
US-5621131-A Conjugated polymers having spiro centers and their use as electroluminescence materials HOECHST AKTIENGESELLSCHAFT (DE) 1997-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240147841-A1 Organic Semiconductive Layer Comprising Phosphine Oxide Compounds ALK, OR10J3, CCNT1 KDM4E 3680/4885MEN1 64/4885LMNA 2421/4885
US-11950496-B2 Organic semiconductive layer comprising phosphine oxide compounds ALK, OR10J3, C1S KDM4E 3742/4885MEN1 64/4885LMNA 2280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.