Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12588809 | 0.90 | OPRD1 (0.59) | OPRD1OPRK1OPRM1LMNAPDE4D | |
| SCHEMBL12306940 | 0.90 | OPRD1 (0.59) | OPRD1OPRK1OPRM1LMNAPDE4D | |
| SCHEMBL12929746 | 0.89 | OPRM1 (0.58) | OPRD1OPRK1OPRM1LMNAPDE4D | |
| SCHEMBL12303427 | 0.89 | OPRD1 (0.72) | OPRD1OPRK1OPRM1LMNAPDE4D | |
| SCHEMBL16312089 | 0.89 | OPRD1 (0.72) | OPRD1OPRK1OPRM1LMNAPDE4D | |
| SCHEMBL14066449 | 0.89 | OPRD1 (0.72) | OPRD1OPRK1OPRM1LMNAPDE4D | |
| SCHEMBL3844397 | 0.89 | OPRD1 (0.72) | OPRD1OPRK1OPRM1LMNAPDE4D | |
| SCHEMBL3844407 | 0.89 | OPRD1 (0.72) | OPRD1OPRK1OPRM1LMNAPDE4D | |
| SCHEMBL22892792 | 0.89 | OPRD1 (0.72) | OPRD1OPRK1OPRM1LMNAPDE4D | |
| SCHEMBL25681504 | 0.89 | OPRD1 (0.72) | OPRD1OPRK1OPRM1LMNAPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149900-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149900-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | FLI1, CDC73, FOS | OPRD1 3594/4885OPRK1 2388/4885OPRM1 2013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.