Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9920121 | 0.89 | OPRK1 (0.50) | OPRK1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13892281 | 0.81 | OPRK1 (0.50) | OPRK1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9920128 | 0.79 | OPRK1 (0.52) | OPRK1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9920132 | 0.78 | OPRK1 (0.50) | OPRK1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9920120 | 0.78 | OPRK1 (0.48) | OPRK1MEN1KMT2AALDH1A1CA12 | |
| SCHEMBL13892280 | 0.78 | OPRK1 (0.60) | OPRK1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13892137 | 0.78 | OPRK1 (0.51) | OPRK1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14147941 | 0.77 | OPRK1 (0.47) | OPRK1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15759421 | 0.77 | DRD2 (0.39) | OPRK1MEN1KMT2AALDH1A1DRD2 | |
| SCHEMBL14819092 | 0.77 | SMN1; SMN2 (0.43) | OPRK1MEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120148586-A1 | GLUCAGON-LIKE PROTEIN-1 RECEPTOR (GLP-1R) AGONISTS FOR TREATING AUTOIMMUNE DISORDERS | CHOU JOYCE CHING TSU (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148586-A1 | GLUCAGON-LIKE PROTEIN-1 RECEPTOR (GLP-1R) AGONISTS FOR TREATING AUTOIMMUNE DISORDERS | GLP1R, GCGR, GIPR | OPRK1 3484/4885MEN1 688/4885KMT2A 3150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.