SCHEMBL9920653

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18267256	0.90	DNMT1 (0.32)	ALDH1A1DNMT1L3MBTL1CDK1CDK4
	SCHEMBL18267251	0.88	CDK1 (0.32)	DNMT1CDK1CDK4CCNB1CCND1
	SCHEMBL13872282	0.87	ALDH1A1 (0.41)	ALDH1A1MAPTMAPK1NPSR1GPR84
	SCHEMBL9921107	0.87	ALDH1A1 (0.42)	ALDH1A1MAPTMAPK1NPSR1GPR84
	SCHEMBL9920649	0.87	ALDH1A1 (0.42)	ALDH1A1MAPTMAPK1NPSR1GPR84
	SCHEMBL9921082	0.87	KDM4E (0.36)	ALDH1A1MAPTMAPK1NPSR1GPR84
	SCHEMBL9920757	0.86	ALDH1A1 (0.41)	ALDH1A1MAPTMAPK1NPSR1GPR84
	SCHEMBL12716640	0.86	ALDH1A1 (0.35)	ALDH1A1MAPTMAPK1NPSR1DNMT1
	SCHEMBL12612038	0.85	KDM4E (0.36)	L3MBTL1CDK4CCND1PGRKDM4E
	SCHEMBL9920669	0.85	ALDH1A1 (0.39)	ALDH1A1MAPTMAPK1NPSR1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.