SCHEMBL9921082

SCHEMBL9921082

CC(C)(C)c1cccc(-c2ccc3ccc4c(-c5ccc(-n6c7ccccc7c7ccccc76)cc5)ccc5ccc2c3c54)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PPARG P37231 5/20 0.35
PPARA Q07869 3/20 0.35
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
KIF11 P52732 2/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
PTAFR P25105 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.32
OPRD1 P41143 3/20 0.31
MAPK14 Q16539 1/20 0.30
NR1H4 Q96RI1 1/20 0.30
GPR84 Q9NQS5 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRK1 P41145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9921042 0.92 KDM4E (0.36) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL9921045 0.91 KIF11 (0.33) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL9921107 0.89 ALDH1A1 (0.42) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL9920649 0.89 ALDH1A1 (0.42) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL9920732 0.88 ALDH1A1 (0.39) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL9921067 0.88 KDM4E (0.37) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL9920757 0.88 ALDH1A1 (0.41) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL9920959 0.87 KDM4E (0.36) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL9920669 0.87 ALDH1A1 (0.39) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL9920653 0.87 ALDH1A1 (0.36) KDM4EATML3MBTL1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463352-B1 Light emitting device material and light emitting device TORAY INDUSTRIES (JP) 2018-05-02 EP disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
EP-2463352-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
EP-2463351-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
EP-1942171-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2008-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090096356-A1 Light-emitting device material and light-emitting device PRMT9, CCNL2, MRPL9 KDM4E 2433/4885ATM 1983/4885L3MBTL1 283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.