SCHEMBL9920899

SCHEMBL9920899

Cc1ccc(-c2cc(-c3cccc4c3oc3ccccc34)c3ccc4cc(C(C)(C)C)cc5ccc2c3c54)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.40
MAPT P10636 3/20 0.39
ALDH1A1 P00352 2/20 0.39
MAOB P27338 2/20 0.37
TNKS O95271 1/20 0.34
PARP1 P09874 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
PARP2 Q9UGN5 1/20 0.34
PRKDC P78527 4/20 0.34
GGPS1 O95749 1/20 0.34
KDM4E B2RXH2 3/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32
HTT P42858 2/20 0.32
PTGES2 Q9H7Z7 1/20 0.32
PGR P06401 1/20 0.31
LMNA P02545 2/20 0.31
TP53 P04637 1/20 0.31
RET P07949 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9920936 0.97 ALOX5 (0.44) ALOX5MAPTALDH1A1MAOBTNKS
SCHEMBL9920902 0.95 ALOX5 (0.45) ALOX5MAPTALDH1A1PRKDCGGPS1
SCHEMBL12380279 0.94 ALOX5 (0.42) ALOX5MAPTALDH1A1PRKDCGGPS1
SCHEMBL9920901 0.93 ALOX5 (0.41) ALOX5MAPTALDH1A1PRKDCGGPS1
SCHEMBL9921014 0.93 ALOX5 (0.41) ALOX5MAPTALDH1A1PRKDCGGPS1
SCHEMBL12380332 0.92 ALOX5 (0.40) ALOX5MAPTALDH1A1PRKDCGGPS1
SCHEMBL9920893 0.91 ALOX5 (0.45) ALOX5ALDH1A1PRKDCGGPS1KDM4E
SCHEMBL12380310 0.91 ALOX5 (0.40) ALOX5MAPTALDH1A1PRKDCGGPS1
SCHEMBL12380277 0.91 ALOX5 (0.40) ALOX5MAPTALDH1A1MAOBPRKDC
SCHEMBL12380297 0.91 ALOX5 (0.42) ALOX5MAPTALDH1A1PRKDCGGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463352-B1 Light emitting device material and light emitting device TORAY INDUSTRIES (JP) 2018-05-02 EP disclosed
EP-1942171-B1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES (JP) 2018-04-18 EP disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
EP-2463352-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
EP-2463351-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
US-7989802-B2 Light emitting device material and light emitting device TORAY INDUSTRIES, INC. (JP) 2011-08-02 US disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-20100038634-A1 LIGHT EMITTING DEVICE MATERIAL AND LIGHT EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2010-02-18 US disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
EP-1942171-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2008-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090096356-A1 Light-emitting device material and light-emitting device PRMT9, CCNL2, MRPL9 ALOX5 1517/4885MAPT 3173/4885ALDH1A1 1929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.