SCHEMBL9920902

SCHEMBL9920902

CC(C)(C)c1cc2ccc3c(-c4ccc(-c5cccc6c5oc5ccccc56)cc4)cc(-c4cccc5c4oc4ccccc45)c4ccc(c1)c2c34

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.45
GGPS1 O95749 1/20 0.38
PRKDC P78527 5/20 0.37
PTGES2 Q9H7Z7 1/20 0.35
PIK3CD O00329 1/20 0.34
PIK3CB P42338 1/20 0.34
HDAC8 Q9BY41 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
CDC14B O60729 2/20 0.32
CDC14A Q9UNH5 2/20 0.32
ATM Q13315 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
MEN1 O00255 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
PGR P06401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12380279 0.97 ALOX5 (0.42) ALOX5GGPS1PRKDCPTGES2PIK3CD
SCHEMBL9920901 0.96 ALOX5 (0.41) ALOX5GGPS1PRKDCPTGES2PIK3CD
SCHEMBL12380298 0.96 ALOX5 (0.45) ALOX5GGPS1PRKDCPTGES2PIK3CD
SCHEMBL9921014 0.96 ALOX5 (0.41) ALOX5GGPS1PRKDCPTGES2PIK3CD
SCHEMBL9920934 0.96 ALOX5 (0.45) ALOX5GGPS1PRKDCPTGES2PIK3CD
SCHEMBL9920899 0.95 ALOX5 (0.40) ALOX5GGPS1PRKDCPTGES2PIK3CD
SCHEMBL9920935 0.95 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2PIK3CD
SCHEMBL12380332 0.94 ALOX5 (0.40) ALOX5GGPS1PRKDCPTGES2PIK3CD
SCHEMBL12380299 0.94 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2PIK3CD
SCHEMBL9920893 0.94 ALOX5 (0.45) ALOX5GGPS1PRKDCPTGES2PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1942171-B1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES (JP) 2018-04-18 EP disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
EP-2463351-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
EP-2463352-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
US-7989802-B2 Light emitting device material and light emitting device TORAY INDUSTRIES, INC. (JP) 2011-08-02 US disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-20100038634-A1 LIGHT EMITTING DEVICE MATERIAL AND LIGHT EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2010-02-18 US disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
EP-1942171-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2008-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090096356-A1 Light-emitting device material and light-emitting device PRMT9, CCNL2, MRPL9 ALOX5 1517/4885GGPS1 526/4885PRKDC 4330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.