Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14060706 | 1.00 | TSHR (0.43) | TSHRALDH1A1THRBMEN1HTT | |
| SCHEMBL31344068 | 1.00 | TSHR (0.43) | TSHRALDH1A1THRBMEN1HTT | |
| SCHEMBL15270524 | 1.00 | TSHR (0.43) | TSHRALDH1A1THRBMEN1HTT | |
| SCHEMBL11206243 | 1.00 | TSHR (0.43) | TSHRALDH1A1THRBMEN1HTT | |
| SCHEMBL30003935 | 1.00 | TSHR (0.43) | TSHRALDH1A1THRBMEN1HTT | |
| SCHEMBL7136061 | 0.97 | THRB (0.39) | TSHRALDH1A1THRBMEN1HTT | |
| SCHEMBL8923054 | 0.95 | ALDH1A1 (0.48) | TSHRALDH1A1THRBMEN1HTT | |
| SCHEMBL6945403 | 0.95 | ALDH1A1 (0.48) | TSHRALDH1A1THRBMEN1HTT | |
| SCHEMBL9298425 | 0.95 | ALDH1A1 (0.48) | TSHRALDH1A1THRBMEN1HTT | |
| SCHEMBL22295741 | 0.95 | ALDH1A1 (0.48) | TSHRALDH1A1THRBMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337646-A1 | BIOLUMINESCENT DETECTION OF DNA SYNTHESIS | Promega Corporation (US) | 2024-03-20 | — | — | EP | disclosed |
| US-11828753-B2 | Biosensor microarray compositions and methods | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-11-28 | — | — | US | disclosed |
| WO-2023166801-A1 | NOVEL TIME-RESOLVED FLUORESCENCE IMAGING PROBE | 国立大学法人 東京大学 | 2023-09-07 | — | — | WO | disclosed |
| US-11739314-B2 | Nucleic acid-tagged compositions and methods for multiplexed protein-protein interaction profiling | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
| EP-4225122-A1 | ZWITTERIONIC CELL-PERMEANT AND WATER-SOLUBLE RHODAMINE DYES FOR QUANTITATIVE IMAGING APPLICATIONS | Oregon Health & Science University (US) | 2023-08-16 | — | — | EP | disclosed |
| US-20230147145-A1 | NOVEL TUNABLE PHOTOACTIVATABLE SILICON RHODAMINE FLUOROPHORES | SPIROCHROME AG (CH) | 2023-05-11 | — | — | US | disclosed |
| US-20220143183-A1 | PHOTOSWITCHABLE PROTACS AND SYNTHESIS AND USES THEREOF | NEW YORK UNIVERSITY | 2022-05-12 | — | — | US | disclosed |
| WO-2021119149-A1 | COMPOSITIONS AND METHODS FOR BIOLUMINESCENT DETECTION USING MULTIFUNCTIONAL PROBES | PROMEGA CORPORATION (US) | 2021-06-17 | — | — | WO | disclosed |
| US-10983118-B2 | Biosensor microarray compositions and methods | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-04-20 | — | — | US | disclosed |
| EP-3788048-A1 | COELENTERAZINE COMPOUNDS AS NANOLUC SUICIDE SUBSTRATES | Promega Corporation (US) | 2021-03-10 | — | — | EP | disclosed |
| US-10717977-B2 | Nucleic acid-tagged compositions and methods for multiplexed protein-protein interaction profiling | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-07-21 | — | — | US | disclosed |
| US-10351842-B2 | Nucleic acid-guided ordered protein assemblies and methods | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-07-16 | — | — | US | disclosed |
| EP-3304078-A1 | CELL-PERMEABLE, CELL-COMPATIBLE, AND CLEAVABLE LINKERS FOR COVALENT TETHERING OF FUNCTIONAL ELEMENTS | Promega Corporation (US) | 2018-04-11 | — | — | EP | disclosed |
| US-9938523-B2 | Nucleic acid-tagged compositions and methods for multiplexed protein-protein interaction profiling | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-04-10 | — | — | US | disclosed |
| US-20170088830-A1 | NUCLEIC ACID-GUIDED ORDERED PROTEIN ASSEMBLIES AND METHODS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2017-03-30 | — | — | US | disclosed |
| US-9551705-B2 | Compositions and methods for capture of cellular targets of bioactive agents | PROMEGA CORPORATION (US) | 2017-01-24 | — | — | US | disclosed |
| WO-2016196956-A1 | CELL-PERMEABLE, CELL-COMPATIBLE, AND CLEAVABLE LINKERS FOR COVALENT TETHERING OF FUNCTIONAL ELEMENTS | PROMEGA CORPORATION (US) | 2016-12-08 | — | — | WO | disclosed |
| EP-2969435-A1 | SUBSTRATES FOR COVALENT TETHERING OF PROTEINS TO FUNCTIONAL GROUPS OR SOLID SURFACES | Promega Corporation (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151282-A1 | SUBSTRATES FOR COVALENT TETHERING OF PROTEINS TO FUNCTIONAL GROUPS OR SOLID SURFACES | PROMEGA CORPORATION (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2012078559-A2 | SMALL-MOLECULE HYDROPHOBIC TAGGING OF FUSION PROTEINS AND INDUCED DEGRADATION OF SAME | YALE UNIVERSITY (US) | 2012-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220143183-A1 | PHOTOSWITCHABLE PROTACS AND SYNTHESIS AND USES THEREOF | MDM2, UBE3C, CUL1 | TSHR 2647/4885ALDH1A1 4373/4885THRB 2510/4885 |
| US-10351842-B2 | Nucleic acid-guided ordered protein assemblies and methods | NOP10, NOP2, DNA2 | TSHR 4211/4885ALDH1A1 4526/4885THRB 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.