Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19308329 | 0.83 | GGPS1 (0.50) | RAB9AGGPS1MAPTKMT2AIDO1 | |
| SCHEMBL803376 | 0.82 | GGPS1 (0.37) | RAB9AGGPS1MAPTATML3MBTL1 | |
| SCHEMBL15943539 | 0.81 | FDPS (0.34) | GGPS1IDO1HTR2ASLC6A4 | |
| SCHEMBL25039130 | 0.80 | P2RX7 (0.40) | RAB9AMAPTKMT2AP2RX7HPGD | |
| SCHEMBL14565894 | 0.80 | GRIN2D (0.32) | — | |
| SCHEMBL14565885 | 0.79 | ESR1 (0.37) | RAB9AGGPS1KMT2AHTR2ASLC6A4 | |
| SCHEMBL13509645 | 0.78 | RIPK1 (0.35) | P2RX7 | |
| SCHEMBL13552300 | 0.77 | SLC6A4 (0.41) | KMT2ANPSR1HTR2ASLC6A4KCNH2 | |
| SCHEMBL20181909 | 0.77 | DAO (0.43) | MAPTL3MBTL1P2RX7IDO1HTR2A | |
| SCHEMBL12828157 | 0.77 | GGPS1 (0.36) | RAB9AGGPS1MAPTATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210346353-A1 | CD73 INHIBITORS | ARCUS BIOSCIENCES, INC. | 2021-11-11 | — | — | US | disclosed |
| US-20120148534-A1 | METHODS AND COMPOSITIONS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148534-A1 | METHODS AND COMPOSITIONS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION | EIF2AK2, NSUN3, NSUN2 | RAB9A 2617/4885GGPS1 1543/4885MAPT 4569/4885 |
| US-20210346353-A1 | CD73 INHIBITORS | ENTPD5, ENTPD1, NT5E | RAB9A 1921/4885GGPS1 541/4885MAPT 4081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.