Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11586099 | 0.75 | EPHX1 (0.55) | EPHX1ALDH1A1HTTKDM4EL3MBTL1 | |
| SCHEMBL10596294 | 0.75 | LMNA (0.61) | EPHX1ALDH1A1HTTKDM4ENPC1 | |
| SCHEMBL11814215 | 0.74 | ALDH1A1 (0.58) | EPHX1ALDH1A1HTTKDM4EL3MBTL1 | |
| SCHEMBL7749716 | 0.73 | EPHX1 (0.55) | EPHX1ALDH1A1HTTKDM4ENPC1 | |
| SCHEMBL17596717 | 0.73 | EPHX1 (0.55) | EPHX1ALDH1A1HTTKDM4ENPC1 | |
| SCHEMBL17596716 | 0.73 | EPHX1 (0.55) | EPHX1ALDH1A1HTTKDM4ENPC1 | |
| SCHEMBL28914992 | 0.73 | OPRM1 (0.62) | NPC1RAB9AOPRM1OPRD1OPRK1 | |
| SCHEMBL2451040 | 0.73 | EPHX1 (0.75) | EPHX1ALDH1A1HTTKDM4EL3MBTL1 | |
| SCHEMBL8282413 | 0.73 | EPHX1 (0.50) | EPHX1ALDH1A1HTTKDM4ENPC1 | |
| SCHEMBL7610023 | 0.73 | MEN1 (0.51) | ALDH1A1KDM4EL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010185-B1 | DIHYDROTHIENOPYRIMIDINE FOR TREATING INFLAMMATORY DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2012-06-13 | — | — | EP | disclosed |