Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837258 | 0.80 | CA1 (0.52) | KDM4EALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL7957002 | 0.80 | HPGD (0.42) | KDM4ENISCHTSHRCYP1A2CYP3A4 | |
| SCHEMBL9918361 | 0.78 | NISCH (0.43) | ALDH1A1NISCHTSHRARCYP1A2 | |
| SCHEMBL31391961 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTTSHRSLC6A2SLC6A4 | |
| SCHEMBL21056080 | 0.77 | GAA (0.40) | ALDH1A1MAPTTSHRCYP3A4HTR2A | |
| SCHEMBL31490450 | 0.76 | IRAK4 (0.48) | KDM4EALDH1A1NISCHTSHRCYP1A2 | |
| SCHEMBL1592873 | 0.76 | NISCH (0.47) | KDM4ENISCHTSHRCYP1A2CYP3A4 | |
| SCHEMBL104727 | 0.76 | IRAK4 (0.48) | KDM4EALDH1A1NISCHTSHRCYP1A2 | |
| SCHEMBL10588548 | 0.76 | HTR1B (0.44) | KDM4EALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL28795114 | 0.76 | SLC6A2 (0.46) | KDM4EALDH1A1MAPTNISCHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54122726-A | — | — | None | — | — | JP | disclosed |
| US-20120149662-A1 | Heterocyclic Compounds as Janus Kinase Inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| JP-S54122726-A | PLANT GROWTH REGULATOR | SUMITOMO CHEM CO LTD | 1979-09-22 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149662-A1 | Heterocyclic Compounds as Janus Kinase Inhibitors | JAK2, JAK1, JAK3 | KDM4E 477/4885ALDH1A1 1507/4885MAPT 4399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.