Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922004 | 0.80 | KDM4E (0.41) | HPGDNISCHTSHRCYP1A2SLC6A2 | |
| SCHEMBL5254800 | 0.78 | HTR1A (0.43) | HPGDTSHRCYP1A2KMT2AADRA2B | |
| SCHEMBL1592873 | 0.76 | NISCH (0.47) | HPGDNISCHTSHRNOTUMCYP1A2 | |
| SCHEMBL31490450 | 0.76 | IRAK4 (0.48) | HPGDNISCHTSHRCYP1A2SLC6A2 | |
| SCHEMBL104727 | 0.76 | IRAK4 (0.48) | HPGDNISCHTSHRCYP1A2SLC6A2 | |
| SCHEMBL7988779 | 0.76 | SLC6A2 (0.46) | HPGDNISCHTSHRCYP1A2SLC6A2 | |
| SCHEMBL7345604 | 0.76 | HTR1B (0.44) | HPGDCYP1A2SLC6A2CYP2D6SLC6A4 | |
| SCHEMBL8886048 | 0.74 | LMNA (0.40) | TSHRKMT2AHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL4624005 | 0.74 | IRAK4 (0.47) | HPGDNISCHTSHRCYP1A2SLC6A2 | |
| SCHEMBL28883167 | 0.74 | IRAK4 (0.47) | HPGDNISCHTSHRCYP1A2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288091-B1 | COMPOUNDS SUCH AS 2,2,2-TRICHLOROETHYL N-(4-(2-AMINO-4-THIAZOLYL)-PHENYL)CARBAMATE THAT INHIBIT THE HERPES HELCASE-PRIMASE ENZYME COMPLEX | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-11 | — | — | US | disclosed |