Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.73 |
| ▸ | NPC1 | O15118 | 6/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | TGM2 | P21980 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.59 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL2365682 | 0.98 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL11394952 | 0.94 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL3975157 | 0.94 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL29135461 | 0.89 | SAE1 (0.78) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL7454467 | 0.85 | KMT2A (0.72) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL6396790 | 0.84 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL11092496 | 0.84 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| Hydrochloric Acid SCHEMBL9038264 | 0.83 | KMT2A (0.70) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL11721311 | 0.83 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL4058023 | 0.83 | NPC1 (0.56) | RAB9ANPC1SMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630717-B1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | COUNCIL SCIENT IND RES (IN) | 2022-02-09 | — | — | EP | claimed |
| US-10703714-B2 | Process for the synthesis of aromatic carbamates | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-07-07 | — | — | US | claimed |
| US-20200148631-A1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-05-14 | — | — | US | claimed |
| EP-3630717-A1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | Council of Scientific and Industrial Research (IN) | 2020-04-08 | — | — | EP | claimed |
| WO-2018216036-A1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2018-11-29 | — | — | WO | claimed |
| CN-106046100-A | 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl derivatives, methods for the production thereof and the use thereof for treating diseases | 拜耳知识产权有限责任公司 | 2016-10-26 | — | — | CN | claimed |
| EP-2186506-B1 | Teeth cleaning compound containing menthol with reduced bitter sensation | SYMRISE AG (DE) | 2015-09-30 | — | — | EP | claimed |
| EP-2456783-B1 | 17-HYDROXY-17-PENTAFLUORETHYL-ESTRA-4,9(10)-DIEN-11-ETHINYLPHENYL DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES | BAYER IP GMBH (DE) | 2015-08-19 | — | — | EP | claimed |
| EP-1879877-B1 | ANTIMICROBIAL AGENTS | RANBAXY LAB LTD (IN) | 2013-01-02 | — | — | EP | claimed |
| EP-2456783-A2 | 17-HYDROXY-17-PENTAFLUORETHYL-ESTRA-4,9(10)-DIEN-11-ETHINYLPHENYL DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES | Bayer Pharma Aktiengesellschaft (DE) | 2012-05-30 | — | — | EP | claimed |
| US-20090082399-A1 | Carbamate derivatives as positive allosteric modulators of metabotropic glutamate receptors | ADDEX PHARMA SA (CH) | 2009-03-26 | — | — | US | claimed |
| EP-1893200-A2 | CARBAMATE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX Pharma S.A. (CH) | 2008-03-05 | — | — | EP | claimed |
| EP-1799673-A1 | PYRAZOLE DERIVATIVES AS PHOSPHODIESTERASE 4 INHIBITORS | Memory Pharmaceuticals Corporation (US) | 2007-06-27 | — | — | EP | claimed |
| EP-1594835-A4 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS INC (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006123244-A2 | CARBAMATE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2006-11-23 | — | — | WO | claimed |
| US-20060173199-A1 | Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses | HONG BORCHERNG | 2006-08-03 | — | — | US | claimed |
| US-20060154960-A1 | Phosphodiesterase 4 inhibitors | MEMORY PHARMACEUTICALS CORPORATION | 2006-07-13 | — | — | US | claimed |
| WO-2006044528-A1 | PYRAZOLE DERIVATIVES AS PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2006-04-27 | — | — | WO | claimed |
| EP-1594835-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | Auspex Pharmaceuticals, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| WO-2004064745-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS, INC. (US) | 2004-08-05 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082399-A1 | Carbamate derivatives as positive allosteric modulators of metabotropic glutamate receptors | GRM5, GRIK5, GRM1 | RAB9A 723/4885NPC1 2603/4885SMN1; SMN2 3376/4885 |
| US-20200148631-A1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | TYR, DDC, ALK | RAB9A 3127/4885NPC1 4157/4885SMN1; SMN2 4574/4885 |
| US-10703714-B2 | Process for the synthesis of aromatic carbamates | ALK, DDC, TYR | RAB9A 3122/4885NPC1 4118/4885SMN1; SMN2 4611/4885 |
| US-20060154960-A1 | Phosphodiesterase 4 inhibitors | PDE4A, PDE4B, PDE12 | RAB9A 1437/4885NPC1 4728/4885SMN1; SMN2 1922/4885 |
| US-20060173199-A1 | Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses | LSS, DHPS, CYP51A1 | RAB9A 1188/4885NPC1 2068/4885SMN1; SMN2 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.