Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 4/20 | 0.31 |
| ▸ | AKT2 | P31751 | 4/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.31 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12919299 | 0.97 | GRM5 (0.38) | GRM5MAOAMAOBACHEKDM4E | |
| SCHEMBL12919286 | 0.93 | KDM4E (0.36) | GRM5MAOBKDM4EATML3MBTL1 | |
| SCHEMBL9921869 | 0.93 | KDM4E (0.39) | GRM5MAOAMAOBACHEKDM4E | |
| SCHEMBL12919271 | 0.93 | MAOA (0.39) | MAOAMAOBACHEKDM4EATM | |
| SCHEMBL12919298 | 0.91 | GRM5 (0.38) | GRM5KDM4EATML3MBTL1CYP1A2 | |
| SCHEMBL12919277 | 0.90 | CDK4 (0.39) | GRM5MAOAMAOBACHEKDM4E | |
| SCHEMBL969757 | 0.89 | MAOA (0.41) | GRM5MAOAMAOBACHEKDM4E | |
| SCHEMBL12919300 | 0.89 | HSD17B1 (0.38) | GRM5MAOBKDM4EATML3MBTL1 | |
| SCHEMBL12919328 | 0.88 | AKT1 (0.35) | GRM5CYP1A2AKT1AKT2AKT3 | |
| SCHEMBL12919319 | 0.87 | MAOA (0.38) | GRM5MAOAMAOBACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377573-B2 | Compound having substituted pyridyl group and pyridoindole ring structure linked through phenylene group, and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-8377573-B2 | Compound having substituted pyridyl group and pyridoindole ring structure linked through phenylene group, and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2013-02-19 | — | — | US | disclosed |
| EP-2463288-A1 | Compound having substituted pyridyl group and pyridoindole ring structure linked through phenylene group, and organic electroluminescent device | Hodogaya Chemical Co., Ltd. (JP) | 2012-06-13 | — | — | EP | disclosed |
| US-20110006291-A1 | COMPOUND HAVING SUBSTITUTED PYRIDYL GROUP AND PYRIDOINDOLE RING STRUCTURE LINKED THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO. LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20110006291-A1 | COMPOUND HAVING SUBSTITUTED PYRIDYL GROUP AND PYRIDOINDOLE RING STRUCTURE LINKED THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO. LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110006291-A1 | COMPOUND HAVING SUBSTITUTED PYRIDYL GROUP AND PYRIDOINDOLE RING STRUCTURE LINKED THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | KCNH3, KCNH2, CHRNA9 | GRM5 2016/4885MAOA 599/4885MAOB 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.