Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 7/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662277 | 0.86 | BRS3 (0.48) | RORCCNR2BRS3CA1CA2 | |
| SCHEMBL992252 | 0.83 | HRH3 (0.41) | PPARAPPARGCA1CA2MITF | |
| SCHEMBL11426539 | 0.81 | RORC (0.51) | RORCCNR2BRS3CYP4F2CYP4A11 | |
| SCHEMBL14393384 | 0.81 | RORC (0.51) | RORCCNR2BRS3CYP4F2CYP4A11 | |
| SCHEMBL992232 | 0.80 | CYP4F2 (0.57) | RORCCNR2BRS3CYP4F2CYP4A11 | |
| SCHEMBL7046145 | 0.79 | RORC (0.49) | RORCCNR2BRS3CYP4F2CYP4A11 | |
| SCHEMBL8434856 | 0.78 | RORC (0.53) | RORCCNR2PPARAF2F10 | |
| SCHEMBL3587301 | 0.78 | MITF (0.53) | CA1CA2MITF | |
| Hydrochloric Acid SCHEMBL11110222 | 0.77 | RORC (0.48) | RORCCNR2BRS3CYP4F2CYP4A11 | |
| SCHEMBL11045152 | 0.77 | HPGD (0.54) | CA1CA2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633223-B2 | Process for preparation of 2-methyl-2′-phenylpropionic acid derivatives and novel intermediate compounds | YUHAN CORPORATION (KR) | 2014-01-21 | — | — | US | disclosed |
| US-8487106-B2 | Process for preparation of 2-methyl-2′-phenylpropionic acid derivatives and novel intermediate compounds | YUHAN CORPORATION (KR) | 2013-07-16 | — | — | US | disclosed |
| US-20130116439-A1 | PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | YUHAN CORPORATION (KR) | 2013-05-09 | — | — | US | disclosed |
| US-20130116466-A1 | PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | YUHAN CORPORATION (KR) | 2013-05-09 | — | — | US | disclosed |
| US-8367704-B2 | Process for preparation of 2-methyl-2′ phenylpropionic acid derivatives and novel intermediate compounds | YUHAN CORPORATION (KR) | 2013-02-05 | — | — | US | disclosed |
| US-20110009636-A1 | PROCESS FOR THE PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | YUHAN CORPORATION (KP) | 2011-01-13 | — | — | US | disclosed |
| EP-2240464-A2 | PROCESS FOR PREPARATION OF 2-METHYL-2´-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | Yuhan Corporation (KR) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009102155-A2 | PROCESS FOR PREPARATION OF 2-METHYL-2´-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | YUHAN CORPORATION (KR) | 2009-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009636-A1 | PROCESS FOR THE PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | HRH4, HCAR2, HRH1 | RORC 3069/4885CNR2 318/4885BRS3 1732/4885 |
| US-20130116439-A1 | PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | HRH2, HRH4, HNMT | RORC 3248/4885CNR2 280/4885BRS3 1384/4885 |
| US-20130116466-A1 | PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | HRH1, HRH2, HRH4 | RORC 2955/4885CNR2 247/4885BRS3 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.