Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APOB | P04114 | 2/20 | 0.35 |
| ▸ | MTTP | P55157 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922372 | 0.93 | MEN1 (0.40) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL9922184 | 0.92 | MEN1 (0.40) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL12161571 | 0.91 | MEN1 (0.38) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL12161567 | 0.91 | MEN1 (0.38) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL9923251 | 0.90 | RORC (0.37) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL9922404 | 0.90 | LMNA (0.39) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL9923249 | 0.90 | RORC (0.37) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL9922960 | 0.90 | KMT2A (0.40) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL9922832 | 0.89 | KCNH2 (0.37) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL14228354 | 0.89 | KMT2A (0.39) | KMT2AMEN1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | TBXA2R, GP6, P2RY6 | KMT2A 3023/4885MEN1 4499/4885ALDH1A1 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.