Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27643856 | 0.83 | TSHR (0.47) | TRPA1GABRA1GABRB2GABRG2GABRB3 | |
| SCHEMBL6895101 | 0.79 | GABRA1 (0.54) | TRPA1GABRA1GABRB2GABRG2GABRB3 | |
| SCHEMBL9900871 | 0.79 | LMNA (0.36) | TSHRCA1CA2HPGDALDH1A1 | |
| SCHEMBL27744056 | 0.77 | GABRA1 (0.41) | TRPA1GABRA1GABRB2GABRG2GABRB3 | |
| SCHEMBL28256228 | 0.77 | HSPA5 (0.48) | TRPA1GABRA1GABRB2TSHRCA2 | |
| SCHEMBL765679 | 0.77 | HSPA5 (0.48) | TRPA1GABRA1GABRB2TSHRCA2 | |
| SCHEMBL7708166 | 0.76 | LMNA (0.36) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL7111161 | 0.72 | GABRA1 (0.42) | GABRA1GABRB2TSHRHDAC4HDAC2 | |
| SCHEMBL2729699 | 0.72 | HSD17B10 (0.41) | TRPA1GABRA1GABRB2TSHRCA1 | |
| SCHEMBL23841325 | 0.71 | GABRA1 (0.45) | GABRA1GABRB2TSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076877-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |