Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12593841 | 0.88 | AAK1 (0.48) | LTA4HALDH1A1MAPTAAK1KMT2A | |
| SCHEMBL20567481 | 0.86 | LTA4H (0.42) | LTA4HALDH1A1MAPTAAK1GFER | |
| SCHEMBL29437990 | 0.86 | LTA4H (0.42) | LTA4HALDH1A1MAPTAAK1GFER | |
| SCHEMBL9923881 | 0.86 | LTA4H (0.42) | LTA4HALDH1A1MAPTAAK1GFER | |
| SCHEMBL12594172 | 0.86 | LTA4H (0.42) | LTA4HALDH1A1MAPTAAK1GFER | |
| SCHEMBL12593849 | 0.84 | AAK1 (0.42) | LTA4HALDH1A1MAPTAAK1GFER | |
| SCHEMBL12594175 | 0.83 | KMT2A (0.47) | LTA4HALDH1A1MAPTAAK1GFER | |
| SCHEMBL12594100 | 0.83 | ACACA (0.40) | LTA4HALDH1A1MAPTAAK1KMT2A | |
| SCHEMBL17549698 | 0.82 | LTA4H (0.64) | LTA4HALDH1A1MAPTGFERRAB9A | |
| SCHEMBL20906310 | 0.81 | AAK1 (0.48) | LTA4HALDH1A1MAPTAAK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076877-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |