Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924259 | 1.00 | CHRM1 (0.38) | CHRM1MCHR1MEN1KMT2APOLB | |
| SCHEMBL17206702 | 1.00 | CHRM1 (0.38) | CHRM1MCHR1MEN1KMT2APOLB | |
| SCHEMBL9924254 | 0.95 | CHRM1 (0.39) | CHRM1MCHR1MEN1KMT2APOLB | |
| SCHEMBL9924084 | 0.94 | GRM4 (0.35) | MEN1KMT2AGRM4ALDH1A1EPHX2 | |
| SCHEMBL9924082 | 0.93 | CHRM1 (0.38) | CHRM1MEN1KMT2APOLBGRM4 | |
| SCHEMBL17206629 | 0.93 | CHRM1 (0.38) | CHRM1MEN1KMT2APOLBGRM4 | |
| SCHEMBL9924087 | 0.93 | HSD11B1 (0.39) | MEN1KMT2AGRM4ALDH1A1EPHX2 | |
| SCHEMBL9924255 | 0.92 | GRM4 (0.36) | MEN1KMT2AGRM4ALDH1A1EPHX2 | |
| SCHEMBL17206710 | 0.91 | MEN1 (0.38) | MCHR1MEN1KMT2APOLBGRM4 | |
| SCHEMBL9924077 | 0.90 | GRM4 (0.38) | KMT2AGRM4ALDH1A1EPHX2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |