Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | MC5R | P33032 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924087 | 0.95 | HSD11B1 (0.39) | GRM4EPHX2MC5RKMT2AHSD11B1 | |
| SCHEMBL9924077 | 0.93 | GRM4 (0.38) | GRM4EPHX2KMT2AHSD11B1MAPT | |
| SCHEMBL9924329 | 0.92 | SLC6A9 (0.40) | EPHX2KMT2AHSD11B1MAPTSLC6A9 | |
| SCHEMBL17206702 | 0.92 | CHRM1 (0.38) | GRM4EPHX2MC5RKMT2AHSD11B1 | |
| SCHEMBL9924228 | 0.92 | CHRM1 (0.38) | GRM4EPHX2MC5RKMT2AHSD11B1 | |
| SCHEMBL9924259 | 0.92 | CHRM1 (0.38) | GRM4EPHX2MC5RKMT2AHSD11B1 | |
| SCHEMBL9924069 | 0.92 | GRM4 (0.38) | GRM4MC5RKMT2AMAPTUSP2 | |
| SCHEMBL9924084 | 0.91 | GRM4 (0.35) | GRM4EPHX2MC5RKMT2AHSD11B1 | |
| SCHEMBL9924256 | 0.90 | NPC1 (0.36) | GRM4EPHX2KMT2ADRD2MEN1 | |
| SCHEMBL9924254 | 0.90 | CHRM1 (0.39) | GRM4EPHX2MC5RKMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |