Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923860 | 0.93 | P2RX7 (0.40) | CHRM1ALDH1A1TSHRMCHR1AR | |
| SCHEMBL9924270 | 0.92 | HPGD (0.40) | CHRM1ALDH1A1HPGDL3MBTL1MCHR1 | |
| SCHEMBL9923859 | 0.91 | CHRM1 (0.41) | CHRM1ALDH1A1TSHRMCHR1ROCK2 | |
| SCHEMBL17206723 | 0.91 | EPHX2 (0.43) | CHRM1ALDH1A1KDM4EROCK2ROCK1 | |
| SCHEMBL9923858 | 0.90 | ALDH1A1 (0.41) | CHRM1TDP1ALDH1A1TSHRMCHR1 | |
| SCHEMBL9924064 | 0.89 | CHRM1 (0.40) | CHRM1MCHR1ROCK2ROCK1CYP2C9 | |
| SCHEMBL9923856 | 0.88 | CHRM1 (0.42) | CHRM1ALDH1A1TSHRMCHR1ROCK2 | |
| SCHEMBL9924156 | 0.87 | CHRM1 (0.45) | CHRM1ALDH1A1MCHR1ARCYP2C9 | |
| SCHEMBL17206627 | 0.87 | KMT2A (0.42) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL9924066 | 0.86 | CHRM1 (0.41) | CHRM1ALDH1A1TSHRMCHR1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |