Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | EBP | Q15125 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901794 | 0.73 | CA1 (0.39) | RORCESR1ESR2PTGS2MEN1 | |
| SCHEMBL9901793 | 0.73 | CA1 (0.39) | RORCESR1ESR2PTGS2MEN1 | |
| SCHEMBL167454 | 0.72 | KDM4E (0.59) | SIGMAR1MEN1KMT2AP4HTM | |
| SCHEMBL29472019 | 0.72 | KDM4E (0.59) | SIGMAR1MEN1KMT2AP4HTM | |
| SCHEMBL244767 | 0.72 | KDM4E (0.59) | SIGMAR1MEN1KMT2AP4HTM | |
| SCHEMBL4326059 | 0.72 | PTGS2 (0.55) | RORCPTGS2MEN1ALOX15TSHR | |
| SCHEMBL5587360 | 0.71 | SIGMAR1 (0.44) | SIGMAR1ESR1ESR2MEN1GRIN2D | |
| SCHEMBL5587356 | 0.71 | SIGMAR1 (0.44) | SIGMAR1ESR1ESR2MEN1GRIN2D | |
| SCHEMBL808900 | 0.71 | SIGMAR1 (0.46) | SIGMAR1ESR1ESR2MEN1GRIN2D | |
| SCHEMBL2229008 | 0.71 | SIGMAR1 (0.46) | SIGMAR1ESR1ESR2MEN1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076898-A1 | TRIAZOLE DERIVATIVES AS WNT SIGNALING PATHWAY INHIBITORS | OSLO UNIVERSITY HOSPITAL HF (NO) | 2012-06-14 | — | — | WO | disclosed |