Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808900 | 1.00 | SIGMAR1 (0.46) | SIGMAR1ESR2ESR1GRIN2DGRIN3B | |
| SCHEMBL5693829 | 0.98 | SIGMAR1 (0.45) | SIGMAR1ESR2ESR1GRIN2DGRIN3B | |
| SCHEMBL5606687 | 0.98 | SIGMAR1 (0.45) | SIGMAR1ESR2ESR1GRIN2DGRIN3B | |
| SCHEMBL5588687 | 0.98 | SIGMAR1 (0.45) | SIGMAR1ESR2ESR1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL3290040 | 0.96 | SIGMAR1 (0.44) | SIGMAR1ESR2ESR1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL1539025 | 0.96 | SIGMAR1 (0.44) | SIGMAR1ESR2ESR1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL1539024 | 0.96 | SIGMAR1 (0.46) | SIGMAR1ESR2ESR1GRIN2DGRIN3B | |
| SCHEMBL15082888 | 0.93 | SIGMAR1 (0.41) | SIGMAR1ESR2ESR1GRIN2DGRIN3B | |
| SCHEMBL15082897 | 0.93 | SIGMAR1 (0.45) | SIGMAR1ESR2ESR1GRIN2DGRIN3B | |
| SCHEMBL12266826 | 0.93 | SIGMAR1 (0.41) | SIGMAR1ESR2ESR1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-B1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | EP | claimed |
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | claimed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | claimed |
| WO-2011089000-A1 | PROCESS FOR THE PREPARATION OF ETHYLENE COPOLYMER COMPOSITIONS IN THE PRESENCE OF AN OLIGOMERIZATION CATALYST | BASELL POLYOLEFINE GMBH (DE) | 2011-07-28 | — | — | WO | disclosed |
| US-7547783-B2 | Transition metal complexes | SHELL OIL COMPANY (US) | 2009-06-16 | — | — | US | disclosed |
| EP-1919850-B1 | NITRO SUBSTITUTED ALPHA-OLEFIN SYNTHESIS CATALYSTS | DU PONT (US) | 2009-03-18 | — | — | EP | disclosed |
| US-20080194768-A1 | Nitro substituted alpha -olefin synthesis catalysts | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-08-14 | — | — | US | disclosed |
| EP-1943281-A1 | HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE | Basell Polyolefine GmbH (DE) | 2008-07-16 | — | — | EP | disclosed |
| EP-1919850-A2 | NITRO SUBSTITUTED ALPHA-OLEFIN SYNTHESIS CATALYSTS | E.I.Du pont de nemours and company (US) | 2008-05-14 | — | — | EP | disclosed |
| EP-1740598-B1 | TRANSITION METAL COMPLEXES | SHELL INT RESEARCH (NL) | 2008-03-05 | — | — | EP | disclosed |
| US-7297806-B2 | Ethylene oligomerization catalyst comprising an iron complex of a 2,6-bis(1-(phenylimino)ethyl)pyridine ligand of given formula with a Lewis acid such as methylalumoxane; forms alpha-olefins of formula H-(CH2-CH2)q-CH=CH2 q=1-18 | EI DU PONT DE NEMOURS AND COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| US-20030144514-A1 | Non-symmetrical ligands and catalyst systems thereof for ethylene oligomerisation to linear alpha olefins | DE BOER ERIC JOHANNES MARIA (NL) | 2003-07-31 | — | — | US | disclosed |
| US-20030050494-A1 | Manufacture of alpha-olefins | BROOKHART MAURICE S (US) | 2003-03-13 | — | — | US | disclosed |
| US-20030036615-A1 | Manufacture of alpha-olefins | BROOKHART MAURICE S (US) | 2003-02-20 | — | — | US | disclosed |
| EP-0994831-B1 | MANUFACTURE OF ALPHA-OLEFINS | DU PONT (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6489497-B1 | SELECTED 2,6-PYRIDINEDICARBOXALDEHYDE BISIMINES USEFUL AS TRIDENTATE LIGANDS FOR ETHYLENE OLIGOMERIZATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-12-03 | — | — | US | disclosed |
| US-20020128409-A1 | Process for the co-oligomerisation of ethylene and alpha olefins | SHELL OIL COMPANY | 2002-09-12 | — | — | US | disclosed |
| US-20020028941-A1 | Ligands and catalyst systems thereof for ethylene oligomerisation to linear alpha olefins | SHELL OIL COMPANY | 2002-03-07 | — | — | US | disclosed |
| US-20020016425-A1 | Non-symmetrical ligands and catalyst systems thereof for ethylene oligomerisation to linear alpha olefins | SHELL OIL COMPANY | 2002-02-07 | — | — | US | disclosed |
| US-6103946-A | BY CONTACTING ETHYLENE WITH AN IRON COMPLEX OF A SELECTED 2,6-PYRIDINEDICARBOXALDEHYDE BISIMINE OR A SELECTED 2,6-DIACYLPYRIDINE BISIMINE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050494-A1 | Manufacture of alpha-olefins | ALOX12, ALOX15B, AP1M1 | SIGMAR1 1623/4885ESR2 533/4885ESR1 830/4885 |
| US-20080194768-A1 | Nitro substituted alpha -olefin synthesis catalysts | ETFA, CBR1, ETFB | SIGMAR1 441/4885ESR2 611/4885ESR1 707/4885 |
| US-20030144514-A1 | Non-symmetrical ligands and catalyst systems thereof for ethylene oligomerisation to linear alpha olefins | OPRM1, AP1M1, OPRD1 | SIGMAR1 21/4885ESR2 686/4885ESR1 935/4885 |
| US-20020028941-A1 | Ligands and catalyst systems thereof for ethylene oligomerisation to linear alpha olefins | OPRM1, OPRD1, PYM1 | SIGMAR1 37/4885ESR2 535/4885ESR1 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.