SCHEMBL9926467

SCHEMBL9926467

CN1C(=O)C(N)=C(N)C1=O

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
ATM Q13315 1/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
GSK3A P49840 1/20 0.35
GSK3B P49841 1/20 0.35
MGLL Q99685 1/20 0.35
CASP3 P42574 1/20 0.35
PTGS2 P35354 2/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6850987 0.76 GSK3A (0.44) KMT2AMEN1USP2ATMKEAP1
SCHEMBL23643407 0.76 ALDH1A1 (0.35) KMT2AMEN1ALDH1A1
SCHEMBL23315143 0.74
SCHEMBL22592279 0.69
SCHEMBL441644 0.67 MEN1 (0.47) KMT2AMEN1USP2ATMKEAP1
SCHEMBL23934207 0.67 THRB (0.50) KMT2AMEN1USP2ATMKEAP1
SCHEMBL19159421 0.67 MPO (0.31)
SCHEMBL802733 0.67 ALDH1A1 (0.40) KMT2AMEN1GSK3AGSK3BMGLL
SCHEMBL11414636 0.64 GSK3A (0.35) GSK3AGSK3BMGLLCASP3ALDH1A1
SCHEMBL22342866 0.64 ALDH1A1 (0.35) KMT2AMEN1GSK3AGSK3BMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4306614-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
US-RE46426-E1 Birefringent polymer film with negative optical dispersion MERCK PATENT GMBH (DE) 2017-06-06 US disclosed
WO-2017001043-A1 PROCESS OF PREPARING A LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2017-01-05 WO disclosed
WO-2016184543-A1 REACTIVE MESOGENS MERCK PATENT GMBH (DE) 2016-11-24 WO disclosed
WO-2016184542-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2016-11-24 WO disclosed
EP-2670818-B1 LIQUID CRYSTAL DISPLAYS WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2016-10-05 EP disclosed
EP-2557140-B1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2016-09-21 EP disclosed
EP-2243812-B2 Liquid crystal display MERCK PATENT GMBH (DE) 2016-09-07 EP disclosed
US-20160244671-A1 METHOD OF PREPARING A BIREFRINGENT POLYMER FILM MERCK PATENT GMBH (DE) 2016-08-25 US disclosed
US-20160215216-A1 POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM MERCK PATENT GMBH (DE) 2016-07-28 US disclosed
EP-2243812-B1 Liquid crystal display MERCK PATENT GMBH (DE) 2012-06-13 EP disclosed
EP-2218764-B1 Chiral reactive mesogen mixture MERCK PATENT GMBH (DE) 2012-01-18 EP disclosed
WO-2011050896-A1 POLYMERISABLE LC MATERIAL AND POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION MERCK PATENT GMBH (DE) 2011-05-05 WO disclosed
WO-2009030332-A1 CALAMITIC MESOGENIC COMPOUNDS MERCK PATENT GMBH (DE) 2009-03-12 WO disclosed
WO-2009030322-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2009-03-12 WO disclosed
WO-2008119427-A1 BIREFRINGENT POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION MERCK PATENT GMBH (DE) 2008-10-09 WO disclosed
WO-2007115639-A1 CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS MERCK PATENT GMBH (DE) 2007-10-18 WO disclosed
WO-2007059849-A1 REGIOREGULAR POLYSELENOPHENES MERCK PATENT GMBH (DE) 2007-05-31 WO disclosed
WO-2007039104-A1 CHIRAL COMPOUNDS MERCK PATENT GMBH (DE) 2007-04-12 WO disclosed
WO-2007039105-A1 CHIRAL COMPOUNDS MERCK PATENT GMBH (DE) 2007-04-12 WO disclosed