Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 6/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9927118 | 1.00 | TTR (0.72) | TTRPTGS1KDM4ELMNACYP1A1 | |
| SCHEMBL15481234 | 0.86 | TTR (0.52) | TTRPTGS1KDM4ELMNACYP1A1 | |
| SCHEMBL9927101 | 0.84 | TTR (1.00) | TTRPTGS1KDM4ELMNACYP1A1 | |
| SCHEMBL9927100 | 0.84 | TTR (1.00) | TTRPTGS1KDM4ELMNACYP1A1 | |
| SCHEMBL9927124 | 0.80 | TUBB4A (0.78) | TTRPTGS1KDM4ECYP1A1PTGS2 | |
| SCHEMBL9927133 | 0.78 | CA1 (0.57) | TTRPTGS1PTGS2CYP3A4MAPT | |
| SCHEMBL17834014 | 0.78 | TUBB1 (0.63) | CYP1A1PTGS2CYP1A2CYP1B1CYP19A1 | |
| Resveratrol SCHEMBL20603099 | 0.77 | KDM4E (0.91) | TTRPTGS1KDM4ELMNACYP1A1 | |
| Resveratrol SCHEMBL20603098 | 0.77 | KDM4E (0.91) | TTRPTGS1KDM4ELMNACYP1A1 | |
| Resveratrol SCHEMBL19425 | 0.77 | PTGS1 (1.00) | TTRPTGS1KDM4ELMNACYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166592-A1 | BORONIC ACID DERIVATIVES OF RESVERATROL FOR ACTIVATING DEACETYLASE ENZYMES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-16 | — | — | US | disclosed |
| US-20120149663-A1 | BORONIC ACID COMPOSITIONS AND METHODS RELATED TO CANCER | GEORGETOWN UNIVERSITY (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166592-A1 | BORONIC ACID DERIVATIVES OF RESVERATROL FOR ACTIVATING DEACETYLASE ENZYMES | HDAC1, BRDT, HDAC7 | TTR 3429/4885PTGS1 2566/4885KDM4E 1628/4885 |
| US-20120149663-A1 | BORONIC ACID COMPOSITIONS AND METHODS RELATED TO CANCER | RB1, RBBP5, CCNB1 | TTR 4498/4885PTGS1 2098/4885KDM4E 2849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.