Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.78 |
| ▸ | TUBB | P07437 | 3/20 | 0.78 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.78 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.78 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.78 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.78 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.78 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.78 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.78 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.78 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.78 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.78 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.78 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.78 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.78 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.65 |
| ▸ | NQO2 | P16083 | 5/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.65 |
| ▸ | TTR | P02766 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1165303 | 0.88 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1165305 | 0.88 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9927126 | 0.82 | ESR1 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9927115 | 0.81 | CYP1B1 (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9927110 | 0.80 | TTR (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9927118 | 0.80 | TTR (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL17834014 | 0.80 | TUBB1 (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Trismethoxyresveratrol SCHEMBL918739 | 0.79 | CYP1A1 (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Trismethoxyresveratrol SCHEMBL918740 | 0.79 | CYP1A1 (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| 8Z-3,4',5-Trimethoxystilbene SCHEMBL1006207 | 0.79 | CYP1A1 (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166592-A1 | BORONIC ACID DERIVATIVES OF RESVERATROL FOR ACTIVATING DEACETYLASE ENZYMES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-16 | — | — | US | disclosed |
| US-20120149663-A1 | BORONIC ACID COMPOSITIONS AND METHODS RELATED TO CANCER | GEORGETOWN UNIVERSITY (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166592-A1 | BORONIC ACID DERIVATIVES OF RESVERATROL FOR ACTIVATING DEACETYLASE ENZYMES | HDAC1, BRDT, HDAC7 | TUBB4A 1341/4885TUBB 1080/4885TUBA3C 3050/4885 |
| US-20120149663-A1 | BORONIC ACID COMPOSITIONS AND METHODS RELATED TO CANCER | RB1, RBBP5, CCNB1 | TUBB4A 1254/4885TUBB 1304/4885TUBA3C 2907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.