Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23124022 | 0.84 | NPY5R (0.58) | CTRB1BCHEACHENPC1RAB9A | |
| SCHEMBL9039372 | 0.79 | NPC1 (0.47) | CTRB1BCHEACHENPC1RAB9A | |
| SCHEMBL18944040 | 0.72 | ABCB1 (0.59) | BCHEACHENPY5RADRA2BADRA2C | |
| SCHEMBL2721341 | 0.71 | CTRB1 (0.45) | CTRB1NPC1RAB9AALDH1A1 | |
| SCHEMBL7415557 | 0.71 | CTRB1 (0.45) | CTRB1NPC1RAB9AALDH1A1 | |
| SCHEMBL12050814 | 0.71 | BCHE (0.53) | BCHEACHENPY5RADRA2BADRA2C | |
| SCHEMBL23303475 | 0.70 | MAPK1 (0.48) | CTRB1NPC1RAB9ANPY5RALDH1A1 | |
| SCHEMBL23303478 | 0.70 | MAPK1 (0.48) | CTRB1NPC1RAB9ANPY5RALDH1A1 | |
| SCHEMBL517463 | 0.69 | ALDH1A1 (0.60) | NPC1RAB9AALDH1A1THRBCYP2C9 | |
| SCHEMBL2600694 | 0.69 | ALDH1A1 (0.60) | NPC1RAB9AALDH1A1THRBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149911-A1 | DERIVATIVE N-THIOLATED 2-OXAZOLIDINONE ANTIBIOTICS | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149911-A1 | DERIVATIVE N-THIOLATED 2-OXAZOLIDINONE ANTIBIOTICS | TST, NRDC, NUCB2 | CTRB1 3989/4885BCHE 3840/4885ACHE 3672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.