Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9928154 | 0.95 | PARP1 (0.33) | PARP1 | |
| SCHEMBL9928151 | 0.91 | PARP1 (0.34) | PARP1 | |
| SCHEMBL9943081 | 0.89 | PARP1 (0.33) | PARP1PDK2 | |
| SCHEMBL9928155 | 0.87 | PARP1 (0.33) | PARP1 | |
| SCHEMBL9928187 | 0.81 | — | — | |
| SCHEMBL9928180 | 0.80 | PARP1 (0.31) | PARP1 | |
| SCHEMBL9928153 | 0.80 | MTNR1A (0.32) | PARP1 | |
| SCHEMBL9928179 | 0.79 | PARP1 (0.33) | PARP1 | |
| SCHEMBL9928156 | 0.79 | PARP1 (0.30) | PARP1 | |
| SCHEMBL9928161 | 0.79 | PDE4D (0.40) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120145974-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-06-14 | — | — | US | disclosed |
| US-20120145974-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120145974-A1 | CHROMENE COMPOUND | CRY2, CYP2J2, NR0B2 | PARP1 2140/4885PDK2 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.