Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK4 | Q13043 | 2/20 | 0.46 |
| ▸ | STK3 | Q13188 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 5/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 5/20 | 0.44 |
| ▸ | TTBK1 | Q5TCY1 | 3/20 | 0.42 |
| ▸ | TTBK2 | Q6IQ55 | 3/20 | 0.42 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9928304 | 0.93 | DRD4 (0.43) | STK4STK3DRD4DRD2DRD3 | |
| SCHEMBL9943097 | 0.91 | EGFR (0.43) | STK4STK3TTBK1TTBK2BRAF | |
| SCHEMBL9898236 | 0.88 | TTBK1 (0.44) | STK4STK3DRD4DRD2DRD3 | |
| SCHEMBL13471655 | 0.83 | DRD2 (0.41) | STK4STK3DRD4DRD2DRD3 | |
| SCHEMBL9943144 | 0.82 | BRAF (0.45) | STK4STK3TTBK1TTBK2BRAF | |
| SCHEMBL9928317 | 0.82 | EGFR (0.51) | STK4STK3TTBK1TTBK2BRAF | |
| SCHEMBL9928319 | 0.82 | TTBK1 (0.42) | STK4STK3TTBK1TTBK2BRAF | |
| SCHEMBL9943065 | 0.82 | MKNK1 (0.42) | DRD4DRD2DRD3AKT1MKNK1 | |
| SCHEMBL9928318 | 0.81 | EGFR (0.48) | STK4STK3BRAFTNNI3KMKNK1 | |
| SCHEMBL9928320 | 0.80 | EGFR (0.48) | STK4STK3TTBK1TTBK2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511276-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVE | Ube Industries, Ltd. (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-20120149902-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
| US-20120149902-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149902-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVE | ERBB2, EGFR, FGFR1 | STK4 91/4885STK3 139/4885DRD4 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.