Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15028836 | 0.93 | CYP17A1 (0.37) | BACE1KCNH2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL9928446 | 0.91 | MAPT (0.30) | — | |
| SCHEMBL9928422 | 0.90 | MAPT (0.31) | — | |
| SCHEMBL9897952 | 0.89 | BACE1 (0.33) | BACE1KCNH2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL16705198 | 0.89 | CYP17A1 (0.34) | BACE1KCNH2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL9928402 | 0.86 | MAPT (0.31) | — | |
| SCHEMBL9928456 | 0.83 | — | — | |
| SCHEMBL9899115 | 0.83 | KDM4E (0.34) | BACE1 | |
| SCHEMBL9928447 | 0.81 | AKT1 (0.33) | — | |
| SCHEMBL18099450 | 0.80 | PLA2G2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120145973-A1 | Photochromic Materials That Include Indeno-Fused Naphthopyrans | TRANSITIONS OPTICAL INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120145973-A1 | Photochromic Materials That Include Indeno-Fused Naphthopyrans | NQO1, INTS6, IPO4 | BACE1 3508/4885KCNH2 687/4885CYP17A1 2312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.