Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | BCR | P11274 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16784200 | 0.91 | TRPA1 (0.59) | CYP3A4KDM4ELMNATP53TSHR | |
| SCHEMBL31197199 | 0.91 | TRPA1 (0.59) | CYP3A4KDM4ELMNATP53TSHR | |
| SCHEMBL29850441 | 0.91 | CYP3A4 (0.52) | CYP3A4KDM4ELMNATP53TSHR | |
| SCHEMBL30543062 | 0.91 | CYP3A4 (0.52) | CYP3A4KDM4ELMNATP53TSHR | |
| SCHEMBL9954880 | 0.89 | SLC6A4 (0.46) | CYP3A4KDM4ELMNATP53TSHR | |
| SCHEMBL9954884 | 0.89 | SLC6A4 (0.46) | CYP3A4KDM4ELMNATP53TSHR | |
| SCHEMBL9005279 | 0.81 | TAAR1 (0.53) | CYP3A4KDM4ELMNATP53TSHR | |
| SCHEMBL13181157 | 0.81 | KDM4E (0.55) | CYP3A4KDM4ELMNATP53TSHR | |
| SCHEMBL11429370 | 0.81 | CYP3A4 (0.57) | CYP3A4KDM4ELMNATP53TSHR | |
| SCHEMBL12479217 | 0.81 | KDM4E (0.55) | CYP3A4KDM4ELMNATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149769-A1 | Thiocarbonates as Anti-Inflammatory and Antioxidant Compounds Useful For Treating Metabolic Disorders | GENMEDICA THERAPEUTICS SL (ES) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149769-A1 | Thiocarbonates as Anti-Inflammatory and Antioxidant Compounds Useful For Treating Metabolic Disorders | CPT1B, LTC4S, TXNRD2 | CYP3A4 4247/4885KDM4E 4746/4885LMNA 521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.