Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.61 |
| ▸ | NQO2 | P16083 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11506232 | 0.89 | SRD5A2 (0.58) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL1962189 | 0.88 | CYP1A2 (0.69) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL15988788 | 0.87 | CTNNB1 (0.67) | TSHRNQO2ALDH1A1CES2MAPT | |
| SCHEMBL3962287 | 0.86 | CYP1A2 (0.71) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL8937269 | 0.84 | NQO2 (0.56) | SRD5A2NQO2CES2MAPTPOLB | |
| SCHEMBL8937272 | 0.84 | NQO2 (0.56) | SRD5A2NQO2CES2MAPTPOLB | |
| SCHEMBL8937264 | 0.84 | NQO2 (0.56) | SRD5A2NQO2CES2MAPTPOLB | |
| SCHEMBL7485522 | 0.84 | SRD5A2 (0.68) | CYP1A2CYP3A4SRD5A2ALDH1A1GAA | |
| SCHEMBL1237189 | 0.82 | SRD5A2 (0.79) | CYP1A2CYP3A4SRD5A2ALDH1A1CES2 | |
| SCHEMBL4710822 | 0.82 | MEN1 (0.54) | CYP1A2CYP3A4SRD5A2NQO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651912-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2018-10-03 | — | — | EP | disclosed |
| US-9034219-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2015-05-19 | — | — | US | disclosed |
| US-20120156521-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120156521-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | CRY2, CRY1, PPOX | CYP1A2 139/4885CYP3A4 595/4885CYP2C9 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.