SCHEMBL992920

SCHEMBL992920

CCc1nc(C)c(-c2ncc[nH]2)[nH]1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.40
ADORA1 P30542 3/20 0.37
ADORA2A P29274 2/20 0.37
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP19A1 P11511 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TP53 P04637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
DDAH1 O94760 1/20 0.35
MTOR P42345 1/20 0.34
ADK P55263 1/20 0.34
TAAR1 Q96RJ0 3/20 0.34
HTR1A P08908 1/20 0.34
PDE4A P27815 2/20 0.34
PDE4B Q07343 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30921502 0.74 TAAR1 (0.48) NISCHADORA1ADORA2ACYP1A2CYP3A4
SCHEMBL6763113 0.69 L3MBTL1 (0.44) CYP1A2TP53L3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL7513420 0.67 MEN1 (0.30) TP53SMN1; SMN2
SCHEMBL131702 0.67
SCHEMBL19116734 0.67 L3MBTL1 (0.61) ADORA1ADORA2ATP53L3MBTL1ALDH1A1
SCHEMBL12472696 0.66 ADORA2A (0.33) NISCHADORA1ADORA2ACYP1A2CYP3A4
SCHEMBL5448437 0.66 NISCH (0.46) NISCHADORA1ADORA2ACYP1A2CYP3A4
SCHEMBL4397237 0.65
Water SCHEMBL7137776 0.65 TAAR1 (0.53) ALDH1A1SMN1; SMN2TAAR1HTR1A
Iodide SCHEMBL633203 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0176475-A2 Compositions for powder coating CIBA-GEIGY AG (CH) 1986-04-02 EP claimed
US-20240166899-A1 PREPARING METHOD FOR BRANCHED VEGETABLE OIL-BASED PHOTOSENSITIVE RESIN AND UV CURING GLASS INK CHINA WEST NORMAL UNIVERSITY (CN) 2024-05-23 US disclosed
US-20110012315-A1 FLUORORUBBER-METAL LAMINATE GASKET MATERIAL NOK CORPORATION (JP) 2011-01-20 US disclosed