SCHEMBL6763113

SCHEMBL6763113

CCc1nc(C)c(-c2ccccn2)[nH]1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.44
TP53 P04637 2/20 0.44
DDAH1 O94760 1/20 0.41
KDM4E B2RXH2 6/20 0.41
LMNA P02545 4/20 0.41
METAP1 P53582 4/20 0.41
CCR1 P32246 2/20 0.41
CCR5 P51681 2/20 0.41
CCR8 P51685 2/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
BLM P54132 1/20 0.41
HIF1A Q16665 1/20 0.41
DOHH Q9BU89 1/20 0.41
P4HTM Q9NXG6 1/20 0.41
CBFB Q13951 5/20 0.40
SMN1; SMN2 Q16637 5/20 0.40
NPC1 O15118 5/20 0.40
TDP1 Q9NUW8 3/20 0.40
METAP2 P50579 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4766017 0.80 KDM4E (0.46) L3MBTL1TP53KDM4ELMNAMETAP1
SCHEMBL19116734 0.76 L3MBTL1 (0.61) L3MBTL1TP53DDAH1KDM4ELMNA
SCHEMBL6761705 0.76 TGFBR1 (0.44) L3MBTL1KDM4ELMNAMETAP1CBFB
SCHEMBL10873517 0.72 GLA (0.43) L3MBTL1TP53DDAH1KDM4ELMNA
SCHEMBL19935423 0.71 CBFB (0.47) L3MBTL1TP53KDM4ELMNAMETAP1
SCHEMBL19116703 0.70 NPY5R (0.46) L3MBTL1TP53KDM4ELMNAMETAP1
SCHEMBL23105410 0.70 CBFB (0.50) L3MBTL1TP53DDAH1KDM4ELMNA
SCHEMBL10565904 0.70 SMN1; SMN2 (0.48) L3MBTL1TP53KDM4ELMNAMETAP1
SCHEMBL7370953 0.70 MGAM (0.49) L3MBTL1KDM4ELMNAMETAP1CBFB
SCHEMBL992920 0.69 NISCH (0.40) L3MBTL1TP53DDAH1CYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4026872-A PHENOLIC CURING AGENTS HITACHI, LTD. (JA) 1977-05-31 US claimed
US-6760989-B2 Decorative badge and method of making DELPHI TECHNOLOGIES, INC. 2004-07-13 US disclosed
US-20030221347-A1 Decorative badge and method of making AUTOLIV DEVELOPMENT AB (SE) 2003-12-04 US disclosed
US-4401499-A LAMINATION SUMITOMO BAKELITE COMPANY LIMITED (JP) 1983-08-30 US disclosed
US-4026872-A PHENOLIC CURING AGENTS HITACHI, LTD. (JA) 1977-05-31 US disclosed
US-4026872-A PHENOLIC CURING AGENTS HITACHI, LTD. (JA) 1977-05-31 US disclosed
US-3984376-A Thermosetting resin compositions prepared from isocyanates and epoxyphenols HITACHI, LTD. (JA) 1976-10-05 US disclosed