Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9930468 | 0.83 | — | — | |
| SCHEMBL9930490 | 0.78 | MAOA (0.34) | HTR1DMAOAMAOBCYP2C19 | |
| SCHEMBL9930178 | 0.77 | MAOA (0.35) | HTR1DMAOAMAOB | |
| SCHEMBL9929913 | 0.72 | IKBKE (0.32) | — | |
| SCHEMBL9930160 | 0.72 | KCNJ1 (0.36) | — | |
| SCHEMBL9930231 | 0.71 | — | — | |
| SCHEMBL9929978 | 0.71 | KCNH2 (0.39) | — | |
| SCHEMBL9929884 | 0.71 | MAOA (0.42) | MAOAMAOB | |
| SCHEMBL9930234 | 0.71 | MAOA (0.35) | MAOAMAOBCYP2C19 | |
| SCHEMBL9930282 | 0.71 | HDAC6 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9046735-B2 | Method and system for determining second-order nonlinear optical coefficients | SELEX SISTEMI INTEGRATI S.P.A. (IT) | 2015-06-02 | — | — | US | claimed |
| US-20120158366-A1 | METHOD AND SYSTEM FOR DETERMINING SECOND-ORDER NONLINEAR OPTICAL COEFFICIENTS | SELEX SISTEMI INTEGRATI S.P.A. (IT) | 2012-06-21 | — | — | US | claimed |
| US-20120157434-A1 | Antimicrobial heterocyclic compounds for treatment of bacterial infections | CSO of MicuRx Pharmaceuticals, Inc. | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157434-A1 | Antimicrobial heterocyclic compounds for treatment of bacterial infections | NISCH, NOD1, NQO1 | HTR1D 3403/4885MAOA 1058/4885MAOB 761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.