Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28222168 | 0.76 | LMNA (0.49) | LMNAMAPTHTTKMT2AMEN1 | |
| SCHEMBL8023046 | 0.74 | MAPT (0.74) | LMNAMAPTHTTKMT2AMEN1 | |
| SCHEMBL20159060 | 0.73 | P2RX4 (0.56) | LMNAMAPTHTTKMT2AMEN1 | |
| SCHEMBL579598 | 0.72 | USP14 (0.46) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL4639305 | 0.71 | MAPT (0.69) | LMNAMAPTHTTKMT2AMEN1 | |
| SCHEMBL9884403 | 0.71 | EGFR (0.54) | LMNAMAPTHTTKMT2AMEN1 | |
| SCHEMBL27715633 | 0.71 | LMNA (1.00) | LMNAMAPTHTTKMT2AMEN1 | |
| SCHEMBL28222169 | 0.70 | NPC1 (0.59) | LMNAMAPTHTTKMT2AMEN1 | |
| SCHEMBL3205310 | 0.67 | CYP19A1 (0.54) | LMNAMAPTHTTKMT2AMEN1 | |
| SCHEMBL24547737 | 0.67 | LMNA (0.50) | LMNAMAPTHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3304088-B1 | BIOMOLECULES INVOLVED IN ALZHEIMER'S DISEASE | ELECTROPHORETICS LTD (GB) | 2025-07-30 | — | — | EP | claimed |
| EP-3304088-A1 | BIOMOLECULES INVOLVED IN ALZHEIMER'S DISEASE | Electrophoretics Limited (GB) | 2018-04-11 | — | — | EP | claimed |
| US-9763947-B2 | Casein kinase 1delta (CK1delta) inhibitors | ELECTROPHORETICS LIMITED (GB) | 2017-09-19 | — | — | US | claimed |
| WO-2016189163-A1 | BIOMOLECULES INVOLVED IN ALZHEIMER'S DISEASE | ELECTROPHORETICS LIMITED (GB) | 2016-12-01 | — | — | WO | claimed |
| CN-105920010-A | Casein Kinase 1delta (ck 1delta) Inhibitors | 电泳有限公司 | 2016-09-07 | — | — | CN | claimed |
| CN-103298460-B | Casein kinase 1(CK1) inhibitors | ELECTROPHORETICS LTD. (GB) | 2016-06-01 | — | — | CN | claimed |
| US-20160058745-A1 | CASEIN KINASE 1DELTA (CK 1DELTA) INHIBITORS | ELECTROPHORETICS LIMITED (GB) | 2016-03-03 | — | — | US | claimed |
| EP-2651404-B1 | CASEIN KINASE 1DELTA (CK1DELTA) INHIBITORS | ELECTROPHORETICS LTD (GB) | 2015-10-14 | — | — | EP | claimed |
| US-20140018540-A1 | CASEIN KINASE 1DELTA (CK 1DELTA) INHIBITORS | ELECTROPHORETICS LIMITED | 2014-01-16 | — | — | US | claimed |
| EP-2651404-A2 | CASEIN KINASE 1DELTA (CK1DELTA) INHIBITORS | Electrophoretics Limited (GB) | 2013-10-23 | — | — | EP | claimed |
| CN-103298460-A | Casein kinase 1 delta (CK1 delta) inhibitors | ELECTROPHORETICS LTD | 2013-09-11 | — | — | CN | claimed |
| WO-2012080727-A2 | CASEIN KINASE 1DELTA (CK1DELTA) INHIBITORS | ELECTROPHORETICS LIMITED (GB) | 2012-06-21 | — | — | WO | claimed |
| US-20260091025-A1 | BIOMOLECULES INVOLVED IN ALZHEIMER'S DISEASE | ELECTROPHORETICS LIMITED (GB) | 2026-04-02 | — | — | US | disclosed |
| EP-4663754-A2 | BIOMOLECULES INVOLVED IN ALZHEIMER'S DISEASE | Electrophoretics Limited (GB) | 2025-12-17 | — | — | EP | disclosed |
| US-12419871-B2 | Biomolecules involved in Alzheimer's disease | ELECTROPHORETICS LIMITED (GB) | 2025-09-23 | — | — | US | disclosed |
| EP-3304088-B1 | BIOMOLECULES INVOLVED IN ALZHEIMER'S DISEASE | ELECTROPHORETICS LTD (GB) | 2025-07-30 | — | — | EP | disclosed |
| US-20140018540-A1 | CASEIN KINASE 1DELTA (CK 1DELTA) INHIBITORS | ELECTROPHORETICS LIMITED | 2014-01-16 | — | — | US | disclosed |
| EP-2651404-A2 | CASEIN KINASE 1DELTA (CK1DELTA) INHIBITORS | Electrophoretics Limited (GB) | 2013-10-23 | — | — | EP | disclosed |
| CN-103298460-A | Casein kinase 1 delta (CK1 delta) inhibitors | ELECTROPHORETICS LTD | 2013-09-11 | — | — | CN | disclosed |
| WO-2012080727-A2 | CASEIN KINASE 1DELTA (CK1DELTA) INHIBITORS | ELECTROPHORETICS LIMITED (GB) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018540-A1 | CASEIN KINASE 1DELTA (CK 1DELTA) INHIBITORS | CSNK1G1, CSNK1A1, CSNK1D | LMNA 1292/4885MAPT 56/4885HTT 1548/4885 |
| US-20260091025-A1 | BIOMOLECULES INVOLVED IN ALZHEIMER'S DISEASE | PYGB, PACSIN2, PPP3CA | LMNA 2088/4885MAPT 25/4885HTT 2618/4885 |
| US-20160058745-A1 | CASEIN KINASE 1DELTA (CK 1DELTA) INHIBITORS | CSNK1A1, CSNK1G1, CSNK1D | LMNA 1197/4885MAPT 60/4885HTT 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.