Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936085 | 1.00 | GBA1 (0.34) | GBA1MAPK14DGAT1MCHR1HIF1A | |
| SCHEMBL9936081 | 1.00 | GBA1 (0.34) | GBA1MAPK14DGAT1MCHR1HIF1A | |
| SCHEMBL8771837 | 0.87 | MAPK14 (0.41) | GBA1MAPK14DGAT1MCHR1GAA | |
| SCHEMBL1962592 | 0.85 | GBA1 (0.34) | GBA1MAPK14DGAT1MCHR1MAPT | |
| SCHEMBL1962593 | 0.85 | GBA1 (0.34) | GBA1MAPK14DGAT1MCHR1MAPT | |
| SCHEMBL1961233 | 0.84 | ALDH1A1 (0.42) | MAPK14DGAT1MAPT | |
| SCHEMBL1961256 | 0.82 | ALDH1A1 (0.42) | MAPK14DGAT1MAPT | |
| SCHEMBL1961254 | 0.82 | ALDH1A1 (0.42) | MAPK14DGAT1MAPT | |
| SCHEMBL1962066 | 0.81 | MAPT (0.44) | MAPK14MAPTKMT2A | |
| SCHEMBL1962070 | 0.81 | MAPT (0.44) | MAPK14MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3045971-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | Transitions Optical, Inc. (US) | 2016-07-20 | — | — | EP | disclosed |
| EP-2652553-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2016-04-06 | — | — | EP | disclosed |
| EP-2652553-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | Transitions Optical, Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012082383-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |