Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | LDLR | P01130 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1962070 | 0.97 | MAPT (0.44) | ALDH1A1LMNAMAPTMAPK14HDAC3 | |
| SCHEMBL1962066 | 0.97 | MAPT (0.44) | ALDH1A1LMNAMAPTMAPK14HDAC3 | |
| SCHEMBL1961254 | 0.96 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTDGAT1MAPK14 | |
| SCHEMBL1961256 | 0.96 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTDGAT1MAPK14 | |
| SCHEMBL2015238 | 0.87 | CA1 (0.48) | ALDH1A1LMNAMAPTDGAT1HDAC3 | |
| SCHEMBL2015239 | 0.87 | CA1 (0.48) | ALDH1A1LMNAMAPTDGAT1HDAC3 | |
| SCHEMBL1960036 | 0.87 | CA1 (0.48) | ALDH1A1LMNAMAPTDGAT1HDAC3 | |
| SCHEMBL1958394 | 0.87 | CA1 (0.48) | ALDH1A1LMNAMAPTDGAT1HDAC3 | |
| SCHEMBL1962051 | 0.87 | MAPT (0.42) | ALDH1A1LMNAMAPTHDAC3HDAC11 | |
| SCHEMBL12125151 | 0.85 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTDGAT1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3621958-B9 | PHOTOCHROMIC INDENO FUSED PHENANTHRENOPYRAN COMPOUNDS | TRANSITIONS OPTICAL LTD (IE) | 2024-09-25 | — | — | EP | disclosed |
| EP-3621958-B1 | PHOTOCHROMIC INDENO FUSED PHENANTHRENOPYRAN COMPOUNDS | TRANSITIONS OPTICAL LTD (IE) | 2024-07-10 | — | — | EP | disclosed |
| CN-110730778-B | Photochromic indeno-fused phenanthropyran compounds | 光学转变有限公司 | 2023-09-12 | — | — | CN | disclosed |
| US-11453654-B2 | Photochromic indeno fused phenanthrenopyran compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2022-09-27 | — | — | US | disclosed |
| US-20200048216-A1 | Photochromic Indeno Fused Phenanthrenopyran Compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2020-02-13 | — | — | US | disclosed |
| CN-110730778-A | Photochromic indeno-fused phenanthropyran compounds | 光学转变有限公司 | 2020-01-24 | — | — | CN | disclosed |
| EP-3045971-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | Transitions Optical, Inc. (US) | 2016-07-20 | — | — | EP | disclosed |
| EP-2652553-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2016-04-06 | — | — | EP | disclosed |
| EP-2652552-B9 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2016-02-17 | — | — | EP | disclosed |
| EP-2652552-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2015-09-02 | — | — | EP | disclosed |
| EP-2652553-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | Transitions Optical, Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| US-8545984-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8518546-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| WO-2012082383-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20110143141-A1 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2011-06-16 | — | — | US | disclosed |
| US-20110129678-A1 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048216-A1 | Photochromic Indeno Fused Phenanthrenopyran Compounds | ALDH1A2, RB1, INCENP | ALDH1A1 433/4885LMNA 1798/4885MAPT 1822/4885 |
| US-20110143141-A1 | Photochromic compounds and compositions | CCNA1, CRY1, CCNT1 | ALDH1A1 43/4885LMNA 230/4885MAPT 785/4885 |
| US-20110129678-A1 | Photochromic compounds and compositions | CRY2, CRY1, PPOX | ALDH1A1 1243/4885LMNA 657/4885MAPT 573/4885 |
| US-11453654-B2 | Photochromic indeno fused phenanthrenopyran compounds | ALDH1A2, RB1, INCENP | ALDH1A1 433/4885LMNA 1798/4885MAPT 1822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.