Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1962592 | 1.00 | GBA1 (0.34) | GBA1DGAT1MCHR1CYP3A4APP | |
| SCHEMBL9936079 | 0.85 | GBA1 (0.34) | GBA1DGAT1MCHR1MAPK14MAPT | |
| SCHEMBL9936081 | 0.85 | GBA1 (0.34) | GBA1DGAT1MCHR1MAPK14MAPT | |
| SCHEMBL9936085 | 0.85 | GBA1 (0.34) | GBA1DGAT1MCHR1MAPK14MAPT | |
| SCHEMBL1961233 | 0.84 | ALDH1A1 (0.42) | DGAT1CYP2C9MAPK14ALDH1A1LMNA | |
| SCHEMBL1961256 | 0.82 | ALDH1A1 (0.42) | DGAT1CYP2C9MAPK14ALDH1A1LMNA | |
| SCHEMBL1961254 | 0.82 | ALDH1A1 (0.42) | DGAT1CYP2C9MAPK14ALDH1A1LMNA | |
| SCHEMBL1962066 | 0.81 | MAPT (0.44) | CYP2C9MAPK14ALDH1A1LMNAMAPT | |
| SCHEMBL1962070 | 0.81 | MAPT (0.44) | CYP2C9MAPK14ALDH1A1LMNAMAPT | |
| SCHEMBL1963458 | 0.77 | MAPK14 (0.41) | GBA1MAPK14MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518546-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| US-20110143141-A1 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110143141-A1 | Photochromic compounds and compositions | CCNA1, CRY1, CCNT1 | GBA1 2937/4885DGAT1 2710/4885MCHR1 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.