Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 12/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 12/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241257 | 0.81 | ALDH1A1 (0.45) | — | |
| SCHEMBL10173733 | 0.81 | ALDH1A1 (0.45) | — | |
| SCHEMBL241258 | 0.81 | ALDH1A1 (0.45) | — | |
| SCHEMBL23247408 | 0.78 | ALDH1A1 (0.42) | — | |
| SCHEMBL13505317 | 0.77 | HCRTR1 (0.37) | HCRTR1HCRTR2PRCP | |
| SCHEMBL18815238 | 0.77 | OPRD1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL18815239 | 0.77 | OPRD1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL1293417 | 0.77 | HCRTR1 (0.37) | HCRTR1HCRTR2PRCP | |
| SCHEMBL6122177 | 0.75 | CYP3A4 (0.43) | HCRTR1HCRTR2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL750549 | 0.75 | HCRTR1 (0.35) | HCRTR1HCRTR2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678334-A1 | ANTI-VIRAL COMPOUNDS | Abbvie Inc. (US) | 2014-01-01 | — | — | EP | disclosed |
| EP-2368890-B9 | Hepatitis C virus inhibitors | ABBVIE BAHAMAS LTD (BS) | 2013-10-30 | — | — | EP | disclosed |
| EP-2651885-A1 | ANTI-VIRAL COMPOUNDS | Abbvie Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| EP-2368890-B1 | Hepatitis C virus inhibitors | ABBVIE BAHAMAS LTD (BS) | 2013-04-17 | — | — | EP | disclosed |
| WO-2012116257-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. (US) | 2012-08-30 | — | — | WO | disclosed |
| WO-2012083170-A1 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-06-21 | — | — | WO | disclosed |