SCHEMBL9937246

SCHEMBL9937246

COCCCOC(=O)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
RECQL P46063 1/20 0.39
ALDH1A1 P00352 4/20 0.39
CES2 O00748 1/20 0.33
GAA P10253 1/20 0.32
MLYCD O95822 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
EPHX2 P34913 1/20 0.32
ARG1 P05089 1/20 0.32
ARG2 P78540 1/20 0.32
KMT2A Q03164 2/20 0.32
HDAC4 P56524 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28903671 0.89 CES2 (0.34) TSHRALDH1A1CES2TDP1KMT2A
SCHEMBL9937822 0.86 TSHR (0.41) TSHRRECQLALDH1A1CES2GAA
SCHEMBL9937156 0.85 ALDH1A1 (0.38) TSHRRECQLALDH1A1TDP1ARG1
Ammonia Solution, Strong SCHEMBL27732666 0.84 TSHR (0.39) TSHRRECQLALDH1A1CES2MLYCD
SCHEMBL19379541 0.84 CES2 (0.39) TSHRALDH1A1CES2TDP1KMT2A
SCHEMBL17807212 0.81 ABCB11 (0.38) TSHRRECQLALDH1A1CES2MLYCD
SCHEMBL4156534 0.80 POLB (0.41) TSHRALDH1A1GAATDP1ARG1
SCHEMBL196154 0.80 ALDH1A1 (0.54) TSHRALDH1A1CES2TDP1KMT2A
SCHEMBL9937333 0.79 CES2 (0.43) TSHRALDH1A1CES2KMT2AMEN1
SCHEMBL2363984 0.78 CES2 (0.55) TSHRALDH1A1CES2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2652832-A1 BATTERY ELECTROLYTE SOLUTION CONTAINING CERTAIN ESTER-BASED SOLVENTS, AND BATTERIES CONTAINING SUCH AN ELECTROLYTE SOLUTION Dow Global Technologies LLC (US) 2013-10-23 EP disclosed
WO-2012082760-A1 BATTERY ELECTROLYTE SOLUTION CONTAINING CERTAIN ESTER-BASED SOLVENTS, AND BATTERIES CONTAINING SUCH AN ELECTROLYTE SOLUTION DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-21 WO disclosed